MP78-16 STUDY OF MAGNETIC COMPRESSION ANASTOMOSIS IN URETERAL ANASTOMOSIS: AN EXPERIMENTAL STUDY ON ANIMALS

Abstract

You have accessJournal of UrologyCME1 Apr 2023MP78-16 STUDY OF MAGNETIC COMPRESSION ANASTOMOSIS IN URETERAL ANASTOMOSIS: AN EXPERIMENTAL STUDY ON ANIMALS Guoxiong Liu, Lin Yang, Xiaofeng Xu, Xianyang, Feng Ma, Dalin He, Ximin Qiao, and Xianyang Guoxiong LiuGuoxiong Liu More articles by this author , Lin YangLin Yang More articles by this author , Xiaofeng XuXiaofeng Xu More articles by this author , Xianyang Xianyang More articles by this author , Feng MaFeng Ma More articles by this author , Dalin HeDalin He More articles by this author , Ximin QiaoXimin Qiao More articles by this author , and Xianyang Xianyang More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003355.16AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Magnetic compression anastomosis (MCA) has been proved to be a rapid, safe, effective and less complications compared with traditional suture anastomosis. However, there is no application of magnetic surgical technique in urology. In this study, we aim to evaluate the efficacy of MCA in living pigs for ureter anastomosis. METHODS: 10 pigs were purchased from the Animal Experimental Center of Xi 'an Jiaotong University. After the pig was anesthetized, an artificial ureteral stricture model was performed in the upper segment of the ureter. Magnet A was placed retrograde in ureteral stricture via urethra and bladder by cystoscope. Nephrostomy was performed under the guidance of ultrasound, and magnet B was placed anterograde through the kidney to the ureteral stricture. The A-B magnets attract each other at the position of ureteral stricture. The nephrostomy tube was indwelled for 4 weeks. After 4 weeks, nephroscopy was performed to check the anastomosis position and the magnet was removed at the same time. 1 week after the magnet was removed, B-ultrasound examination of the kidney and ureter was performed. The ureter tissues at the anastomotic site were checked and stained with H&E. In the control group, ureteral stricture was modeled similarly. Then, in the open surgery, the stenotic ureter was excised. The severed ureter was anastomosed with absorbable suture, and the double J tube was indwelled. After 3 weeks, the double J tube was removed, and 1 week later, B-ultrasound examination of the kidney and ureter was performed. The ureter tissues at the anastomotic site were stained with HE. RESULTS: In the MCA group, the A-B magnets converged at the ureteral stricture 4 weeks after the operation. After the magnets were removed through the nephroscope, the ureteral stricture was unobstructed. One week after the operation, B-ultrasound examination revealed mild hydronephrosis in the kidney and ureter. HE staining showed smooth mucosa, no bleeding and anastomotic leakage at the anastomotic healing site of ureteral stricture. All tissue layers healed well and there was mild scar healed. In the control group, mild hydronephrosis in the kidney and ureter was found by B-ultrasound examination 1 week after the double J tube was removed. There was no bleeding or anastomotic leakage in the mucosa of the anastomosis. However, suture, scar hyperplasia, fibrous tissue hyperplasia and inflammatory cell infiltration were more obvious in the tissue of the anastomosis. CONCLUSIONS: This preclinical studies proved that MCA technique can achieve rapid ureteral anastomosis in pigs and MCA is an feasible, safe and effective in ureteral anastomosis. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e1138 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Guoxiong Liu More articles by this author Lin Yang More articles by this author Xiaofeng Xu More articles by this author Xianyang More articles by this author Feng Ma More articles by this author Dalin He More articles by this author Ximin Qiao More articles by this author Xianyang More articles by this author Expand All Advertisement PDF downloadLoading ...