MP76-20 IMPACT OF BARIATRIC SURGERY ON OVERACTIVE BLADDER SYMPTOMS IN A COHORT OF OBESE PATIENTS: A PROSPECTIVE INVESTIGATION

Abstract

You have accessJournal of UrologyUrodynamics/Incontinence/Female Urology: Non-neurogenic Voiding Dysfunction1 Apr 2014MP76-20 IMPACT OF BARIATRIC SURGERY ON OVERACTIVE BLADDER SYMPTOMS IN A COHORT OF OBESE PATIENTS: A PROSPECTIVE INVESTIGATION Giovanni Palleschi, Antonio Luigi Pastore, Luigi Silvestri, Andrea Fuschi, Yazan Al Salhi, Davide Moschese, Cristina Maggioni, Andrea Ripoli, and Antonio Carbone Giovanni PalleschiGiovanni Palleschi More articles by this author , Antonio Luigi PastoreAntonio Luigi Pastore More articles by this author , Luigi SilvestriLuigi Silvestri More articles by this author , Andrea FuschiAndrea Fuschi More articles by this author , Yazan Al SalhiYazan Al Salhi More articles by this author , Davide MoscheseDavide Moschese More articles by this author , Cristina MaggioniCristina Maggioni More articles by this author , Andrea RipoliAndrea Ripoli More articles by this author , and Antonio CarboneAntonio Carbone More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.2413AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Epidemiological data show an association between obesity and lower urinary tract symptoms (LUTS), especially urinary frequency, urinary urgency and urinary incontinence. Patients with pathologic obesity satisfying specific criteria may be submitted to bariatric surgery which provides a significant reduction of body mass index (BMI) improving quality of life. The aim of this prospective pilot study was to assess the impact of bariatric surgery in a cohort of obese patients suffering from overactive bladder (OAB) symptoms. METHODS From December 2011 to June 2012, a preliminary cohort of 51 patients was enrolled in the protocol. The population was represented by 38 females and 13 males, aged between 19 and 58 years, mean age was 38□4.5 years. Mean BMI of patients was 43.96□8.3; 65.38% of patients had a BMI> 40. Inclusion criteria were considered: obesity (BMI 30) and OAB symptoms investigated by the short form OAB questionnaire (OAB-q SF). Exclusion criteria were represented by urinary infection (urinanalysis), previous urological or gynaecological surgery, suspicious of neurogenic diseases (neurological examination), genital prolapse, significant post-voiding residue (100 mls, evaluated by bladder ultrasound), evidence of chronic renal disease (serum creatinine 1,5 mg/dl). Patients were evaluated at: 1 week before surgery (baseline) and 90 days after surgery (control), represented by “sleeve gastrectomy”. All patients gave their informed consent to be enrolled in the protocol. Statistical analysis was performed to compare BMI and OAB-q SF scores between baseline and follow-up (Student’s T test). RESULTS 29/51 subjects resulted eligible for the protocol (56.8% of the preliminary cohort, 20 females, 9 males, range age 28-58 years, mean 39±3.7 years). Surgical time was 68±21 minutes. There were no intraoperative or postoperative significant complications. Mean hospital stay was 3±1.3 days. A significant reduction of BMI was provided by surgery (preoperative BMI = 43.9±54.5 vs post-operative BMI = 33.45±8,3; p 0,0001). Furthermore, a significant reduction of OAB-q score was observed at 90 days from surgery. CONCLUSIONS Obese patients present several comorbidities and most of these may differently contribute to develop LUTS, including OAB symptoms. Preliminary data coming from our pilot study show that also urinary symptoms may benefit from BMI reduction provided by bariatric surgery. This investigation shows that OAB is well represented in obese subjects and that symptoms significantly improve after bariatric surgery. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e890 Advertisement Copyright & Permissions© 2014MetricsAuthor Information Giovanni Palleschi More articles by this author Antonio Luigi Pastore More articles by this author Luigi Silvestri More articles by this author Andrea Fuschi More articles by this author Yazan Al Salhi More articles by this author Davide Moschese More articles by this author Cristina Maggioni More articles by this author Andrea Ripoli More articles by this author Antonio Carbone More articles by this author Expand All Advertisement Advertisement PDF DownloadLoading ...