MP74-03 MALE INFERTILITY IS ASSOCIATED WITH SEXUAL DYSFUNCTION, DEPRESSION AND LOW SELF-ESTEEM: PROSPECTIVE, CASE-CONTROL, CLINICAL STUDY.

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Evaluation II1 Apr 2018MP74-03 MALE INFERTILITY IS ASSOCIATED WITH SEXUAL DYSFUNCTION, DEPRESSION AND LOW SELF-ESTEEM: PROSPECTIVE, CASE-CONTROL, CLINICAL STUDY. MURAD BASAR, HAKAN SIRIN, ALTUG SEMIZ, MIRAC TURAN, DERYA BALBAY, and MUAMMER KENDIRCI MURAD BASARMURAD BASAR More articles by this author , HAKAN SIRINHAKAN SIRIN More articles by this author , ALTUG SEMIZALTUG SEMIZ More articles by this author , MIRAC TURANMIRAC TURAN More articles by this author , DERYA BALBAYDERYA BALBAY More articles by this author , and MUAMMER KENDIRCIMUAMMER KENDIRCI More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.2387AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The aim this prospective, case-control study was to assess the impact of male infertility and repeated assisted reproductive techniques (ARTs) on male sexual function, depression and self-esteem. METHODS During a 2-year-period, a total of 432 infertile men and 305 fertile controls (fathered after spontaneous pregnancy) were included into this prospective clinical study. After having a detailed medical history taken and a comprehensive physical exam performed, all probable risk factors, lifestyle measures, and co-morbidities for sexual dysfunction were recorded. Blood gonadotropins, total testosterone, estradiol, and prolactin levels were measured in all subjects in the morning after an overnight fasting. Psychogenic status, self-esteem and erectile function of the participants were assessed using Beck Depression Inventory (BDI), Self-esteem Scores (15th question of the International Index of Erectile Function) and Sexual Health Inventory of Male (SHIM). Two consecutive semen analyses were evaluated according to the WHO 2010 criteria in the infertile men only. Both groups were statistically compared regarding BDI, Self-esteem and SHIM scores, and blood hormone levels. Infertile men were also evaluated regarding the impact of semen parameters, number of ARTs cycles, and outcomes of microTESE procedure (in only azoospermic males). RESULTS Mean ages of both groups were comparable. Sexual function scores in the infertile men were significanly lower than the fertile men (mean 21.5 vs. 22.3, p=0.009). When psychogenic status was evaluated, infertile men were documented significantly higher depression and lower self-esteem scores compared to fertile men (6.9 vs. 2.7, p=0.001 and 3.9 vs. 4.1, p=0.003, respectively). When the impact of repeated ARTs cycles was evaluated by regression analyses, there was a significant positive correlation between repeated ARTs cycles and depression (r=.051,p=0.293), but a negative correlation between repeated ARTs cycles and sexual function (r=-.043,p=0.379), and self-esteem scores (r=-.055,p=0.257. At subgroup analyses, severity of seminal parameters did not exert any significant impact on either depressive symptoms or erectile function. Sperm retrieval with microTESE did not show any significant affect on infertile men as evaluated by SHIM, self-esteem, and BDI questionnaires. CONCLUSIONS This study demonstrated that male infertility was associated with increased depressive symptoms and self-esteem but reduced sexual function compared to fertile men. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e1000-e1001 Advertisement Copyright & Permissions© 2018MetricsAuthor Information MURAD BASAR More articles by this author HAKAN SIRIN More articles by this author ALTUG SEMIZ More articles by this author MIRAC TURAN More articles by this author DERYA BALBAY More articles by this author MUAMMER KENDIRCI More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...