MP71-16 GENERATION DIFFERENCE ON THE ASSOCIATION BETWEEN LOWER URINARY TRACT SYMPTOMS AND LATE-ONSET HYPOGONADISM SYMPTOMS: ANALYSIS OF 1398 HEALTHY YOUNG AND ELDERLY ADULTS

Abstract

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Evaluation and Symptoms1 Apr 2015MP71-16 GENERATION DIFFERENCE ON THE ASSOCIATION BETWEEN LOWER URINARY TRACT SYMPTOMS AND LATE-ONSET HYPOGONADISM SYMPTOMS: ANALYSIS OF 1398 HEALTHY YOUNG AND ELDERLY ADULTS Hiroshi Kiuchi, Tetsuji Soda, Kentaro Takezawa, Shinichiro Fukuhara, Yasushi Miyagawa, Akira Tsujimura, Tetsuya Takao, and Norio Nonomura Hiroshi KiuchiHiroshi Kiuchi More articles by this author , Tetsuji SodaTetsuji Soda More articles by this author , Kentaro TakezawaKentaro Takezawa More articles by this author , Shinichiro FukuharaShinichiro Fukuhara More articles by this author , Yasushi MiyagawaYasushi Miyagawa More articles by this author , Akira TsujimuraAkira Tsujimura More articles by this author , Tetsuya TakaoTetsuya Takao More articles by this author , and Norio NonomuraNorio Nonomura More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.2629AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Aging is known to affect sexual, psychological and physiological functions including lower urinary tract symptoms (LUTS). Recent data suggested that severity of LUTS was associated with that of late-onset hypogonadism (LOH) in elderly men. However, information on the association in young adults is limited. In this study, we evaluated the relationship between LUTS and LOH symptoms in young and elderly adults. METHODS This study included 1398 healthy men ≥20 years; 130 in 20□fs, 519 in 30□fs, 399 in 40□fs, 268 in 50□fs and 82 in 60□fs. LUTS was assessed using I-PSS questionnaire and LOH symptoms was evaluated using Aging Male's Symptoms (AMS) questionnaire with higher score indicating more severe symptoms. LUTS was diagnosed as I-PSSS ≥8. Severity of LUTS was defined by I-PSS-QOL as follows; 0-1 as mild, 2-3 as moderate, and 4-6 as severe. Generalized additive models were used for statistical analysis. RESULTS Total I-PSS score increased with age: LUTS was observed in 3.1% in 20's, 2.7% in 30's, 7.8% in 40's, 15.3% in 50's and 22.0% in 60's (p for trend <0.01) (Fig.1). Mild LUTS was found in 751(54%), and moderate LUTS in 556(40%), severe LUTS in 91(7%). Severity of LOH symptoms increased with increasing LUT severity in any years of age. Moreover, young adults with severe LUTS had more severe LOH symptoms than elderly adults (36.3 vs. 28.5, p<0.05) (Fig. 2); they reported higher psychological and physiological sub-score than elderly men, whereas they reported lower sexual score. CONCLUSIONS Both young and elderly adults with severe LUTS have severe LOH symptoms, but young adults with severe LUTS were more likely to have severe LOH symptoms than elderly adults. Therefore, urologist should take care of hypogonadism symptoms other than LUTS when young adults are presented with LUTS. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e918 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Hiroshi Kiuchi More articles by this author Tetsuji Soda More articles by this author Kentaro Takezawa More articles by this author Shinichiro Fukuhara More articles by this author Yasushi Miyagawa More articles by this author Akira Tsujimura More articles by this author Tetsuya Takao More articles by this author Norio Nonomura More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...