MP70-13 THE EFFECT OF CIRCUMCISION/CONTINUOUS ANTIBIOTIC PROPHYLAXIS ON PREVENTING THE RECURRENCE OF FEBRILE URINARY TRACT INFECTION IN BOYS WITH PRIMARY VESICOURETERAL REFLUX

Abstract

You have accessJournal of UrologyCME1 Apr 2023MP70-13 THE EFFECT OF CIRCUMCISION/CONTINUOUS ANTIBIOTIC PROPHYLAXIS ON PREVENTING THE RECURRENCE OF FEBRILE URINARY TRACT INFECTION IN BOYS WITH PRIMARY VESICOURETERAL REFLUX Fang Chen and Yichen Huang Fang ChenFang Chen More articles by this author and Yichen HuangYichen Huang More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003338.13AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To explore the preventing effect of circumcision and continuous antibiotic prophylaxis on the recurrence of febrile urinary tract infection in boys with primary vesicoureteral reflux. METHODS: The clinical data of 88 boys with primary vesicoureteral reflux diagnosed in our hospital were retrospectively analyzed. The median age of the enrolled children was 10.2 months, and the average age was (15.3±15.9) months. The 88 boys were divided into 4 groups, including 3 cases in the watchful waiting group, 50 cases in the continuous antibiotic prophylaxis group, 22 cases in the circumcision group, and 13 cases in the continuous antibiotic prophylaxis+circumcision group. The follow-up time was 1 to 3 years. The recurrence of febrile urinary tract infection in each group was counted, and the effective conservative treatment strategy was analyzed. RESULTS: There were 21 cases (23.9%) of febrile urinary tract infection recurrence among 88 children, 2 cases (66.7%) in the watchful waiting group, 16 cases (32.0%) in the continuous antibiotic prophylaxis group, and 3 cases in the circumcision group (13.6) %). There was no recurrence in 13 patients in the continuous antibiotic prophylaxis+circumcision group. There was a statistical difference in the recurrence rate between the 4 treatment groups (χ2=10.181, p=0.011). Factorial analysis suggests that circumcision is the main factor in reducing the recurrence of febrile urinary tract infections (p=0.003). CONCLUSIONS: For boys with primary vesicoureteral reflux, circumcision is the main factor in reducing the recurrence of febrile urinary tract infections. Circumcision combined with continuous antibiotic prophylaxis can prevent the recurrence of febrile urinary tract infection to the greatest extent. There is no significant difference between continuous antibiotic prophylaxis and watchful waiting in preventing the recurrence of febrile urinary tract infection. Source of Funding: none © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e1008 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Fang Chen More articles by this author Yichen Huang More articles by this author Expand All Advertisement PDF downloadLoading ...