MP7-01 CAN A NON CONTRAST COMPUTED TOMOGRAPHY FINDING PREDICT DEVELOPMENT OF URINARY CALCULI, CHANCES OF RECURRENT STONE DISEASE AND ASSOCIATED URINE METABOLIC ABNORMALITY – A REVIEW OF 655 PATIENTS

Abstract

You have accessJournal of UrologyImaging/Radiology II1 Apr 2014MP7-01 CAN A NON CONTRAST COMPUTED TOMOGRAPHY FINDING PREDICT DEVELOPMENT OF URINARY CALCULI, CHANCES OF RECURRENT STONE DISEASE AND ASSOCIATED URINE METABOLIC ABNORMALITY – A REVIEW OF 655 PATIENTS Ankush Jairath, Arvind Ganpule, Jigish Vyas, Shashikant Mishra, Ravindra Sabnis, and Mahesh Desai Ankush JairathAnkush Jairath More articles by this author , Arvind GanpuleArvind Ganpule More articles by this author , Jigish VyasJigish Vyas More articles by this author , Shashikant MishraShashikant Mishra More articles by this author , Ravindra SabnisRavindra Sabnis More articles by this author , and Mahesh DesaiMahesh Desai More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.324AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To determine whether renal papillae density using attenuation measurement (HU) on noncontrast Computed Tomography (CT) can predict the development of urinary calculi in stone free patients as well in recurrent stone formers and its role in predicting any associated urinary metabolic abnormality. METHODS In this study we compared renal papillae density using attenuation measurement (HU) on noncontrast Computed Tomography (CT) in stone forming group (SFG) (first time stone formers and recurrent stone formers) with the healthy stone free control group (CG). The SFG inclusion criteria were active stone disease (unilateral or bilateral) diagnosed by abdominal computed tomography. Prospective living kidney donor without active or past history of stone disease formed CG. Papillae tip attenuation was measured using noncontrast CT. Mean Hounsfield density (HU) of 3 caliceal group was calculated for each kidney. 24 hours urinary metabolic evaluation was done wherever deemed necessary. Statistical analysis was done using student’s t- test. RESULTS Total of 665 SFG and 104 CG patients met inclusion criteria. 343 patients had bilateral urolithiasis, 312 patients had unilateral urolithiasis, 52 were recurrent stone former and 38 patients having hyperoxaluria and hypercalciuria each. Mean HU of papillae of SFG was greater than that of CG (29.46± 3.06 Vs 27.71±0.48; p < 0.0001). In unilateral urolithiasis mean HU of papillae of calculus bearing kidney was greater than that of non calculus bearing kidney (29.82± 6.14 Vs 28.17±2.04; p < 0.004) and mean HU of papillae of stone free kidney was greater than that of CG (28.17± 2.04 Vs 27.71±0.48; p < 0.01). Mean HU of papillae of recurrent stone former was greater than that of CG (29.3±2.10 Vs 27.71±0.48, p< 0.05). Mean HU of renal papillae of patients having Hypercalciuria was comparable with that of SFG (29.90±2.31 Vs 29.46±3.06, p>0.05) as was patients having Hyperoxaluria (29.80±2.15 Vs 29.46 ± 3.06, p>0.05). CONCLUSIONS Mean HU of renal papillae was significantly increased in patient with urolithiasis. This holds valid for papillae with or without calculi. There is no significant difference between mean HU of renal papillae density in patients having Hypercalciuria/Hyperoxaluria when compared with stone bearing patients with normal urinary metabolic study. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e65 Advertisement Copyright & Permissions© 2014MetricsAuthor Information Ankush Jairath More articles by this author Arvind Ganpule More articles by this author Jigish Vyas More articles by this author Shashikant Mishra More articles by this author Ravindra Sabnis More articles by this author Mahesh Desai More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...