MP67-03 IMPROVEMENT IN FUNCTIONAL AND ONCOLOGICAL OUTCOME IN LOCALLY ADVANCED PROSTATE CANCER BY ROBOT-ASSISTED RADICAL PROSTATECTOMY WITH 3D-CANCER MAPPING GUIDANCE

Abstract

You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy III (MP67)1 Apr 2020MP67-03 IMPROVEMENT IN FUNCTIONAL AND ONCOLOGICAL OUTCOME IN LOCALLY ADVANCED PROSTATE CANCER BY ROBOT-ASSISTED RADICAL PROSTATECTOMY WITH 3D-CANCER MAPPING GUIDANCE Kazumi Kamoi*, Keita Takimoto, Masato Baba, Wataru Satoh, and Tsuneharu Miki Kazumi Kamoi*Kazumi Kamoi* More articles by this author , Keita TakimotoKeita Takimoto More articles by this author , Masato BabaMasato Baba More articles by this author , Wataru SatohWataru Satoh More articles by this author , and Tsuneharu MikiTsuneharu Miki More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000947.03AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: MRI/US fusion biopsy has shown to improve the localization of index lesion and 3D-Cancer mapping can be created to display index lesions in the prostate whether they are attaching or bulging to the prostatic capsule. 3D-Cancer mapping navigation during robot-assisted radical prostatectomy (RARP) has shown to improve oncological outcome in pT3 disease (Kamoi et al, EAU 2017). The aim of this study was to evaluate the functional and histological outcomes in patients who are suspected to have T3 lesions treated by RARP. METHODS: 3D-Cancer mapping was constructed using Trinity™ (Koelis, France), which was applied to diagnose prostate cancer by MR/US fusion technique. Histological data was added to the 3D-Cancer mapping to display index lesions of the prostate whether they are attaching or bulging to the prostatic capsule and was shown in the “Tile-pro display” during RARP. The information of index tumor was applied to RARP by selection of dissection layer especially near the neurovascular and apical area. A total of 76 patients (38 with pT3 and 38 with pT2) were enrolled to this study to compare postoperative early continence and surgical margin status. RESULTS: All patients were applied nerve-sparing procedure in the side without index lesion attaching to the prostatic capsule. Bilateral, hemi-lateral, and non nerve sparing approach were applied to 56, 18 and 2 case, respectively. Among 38 patients with pT3 disease, 3 patients had positive surgical margin (8%) and all 38 patients with pT2 disease had negative surgical margin. An early continence just after catheter removal (0-1 pad per day) was achieved 23/38 (61%) patients with pT3 disease and 30/38 (79%) patients with pT2 disease (p=0.133). CONCLUSIONS: 3D-Cancer mapping correctly provided location and risk of extra-prostatic extension during dissection of the prostate. 3D-Cancer mapping navigation during RARP could secure a safety margin while maintaining an early continence after surgery in pT3 disease. Source of Funding: None © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e1026-e1026 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Kazumi Kamoi* More articles by this author Keita Takimoto More articles by this author Masato Baba More articles by this author Wataru Satoh More articles by this author Tsuneharu Miki More articles by this author Expand All Advertisement PDF downloadLoading ...