MP64-06 THE AMERICAN SOCIETY OF ANESTHESIOLOGISTS’ (ASA) PHYSICAL STATUS SYSTEM CLASSIFICATION PREDICTED THE RISK OF POSTOPERATIVE COMPLICATIONS AT HOSPITAL DISCHARGE IN 1329 CONSECUTIVE PATIENTS TREATED WITH RADICAL PROSTATECTOMY FOR CLINICAL PROSTATE CANCER

Abstract

You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy VI (MP64)1 Sep 2021MP64-06 THE AMERICAN SOCIETY OF ANESTHESIOLOGISTS’ (ASA) PHYSICAL STATUS SYSTEM CLASSIFICATION PREDICTED THE RISK OF POSTOPERATIVE COMPLICATIONS AT HOSPITAL DISCHARGE IN 1329 CONSECUTIVE PATIENTS TREATED WITH RADICAL PROSTATECTOMY FOR CLINICAL PROSTATE CANCER Riccardo Rizzetto, Antonio Benito Porcaro, Nelia Amigoni, Alessandro Tafuri, Clara Cerrato, Alberto Bianchi, Sebastian Gallina, Rossella Orlando, Alessandra Gozzo, Filippo Milgliorini, Stefano Zecchini Antoniolli, Carmelo Monaco, Vincenzo De Marco, Matteo Brunelli, Maria Angela Cerruto, Enrico Polati, and Alessandro Antonelli Riccardo RizzettoRiccardo Rizzetto More articles by this author , Antonio Benito PorcaroAntonio Benito Porcaro More articles by this author , Nelia AmigoniNelia Amigoni More articles by this author , Alessandro TafuriAlessandro Tafuri More articles by this author , Clara CerratoClara Cerrato More articles by this author , Alberto BianchiAlberto Bianchi More articles by this author , Sebastian GallinaSebastian Gallina More articles by this author , Rossella OrlandoRossella Orlando More articles by this author , Alessandra GozzoAlessandra Gozzo More articles by this author , Filippo MilglioriniFilippo Milgliorini More articles by this author , Stefano Zecchini AntoniolliStefano Zecchini Antoniolli More articles by this author , Carmelo MonacoCarmelo Monaco More articles by this author , Vincenzo De MarcoVincenzo De Marco More articles by this author , Matteo BrunelliMatteo Brunelli More articles by this author , Maria Angela CerrutoMaria Angela Cerruto More articles by this author , Enrico PolatiEnrico Polati More articles by this author , and Alessandro AntonelliAlessandro Antonelli More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002104.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To investigate on associations of the American Society of Anesthesiologists’ (ASA) physical status system with features related to clinical prostate cancer (PCa patients) treated with radical prostatectomy (RP) in a large and contemporary cohort operated in a tertiary referral center. METHODS: In a period ranging from January 2013 to October 2020, 1329 patients were evaluated. The ASA system was computed by anesthesiologists dedicated to urological procedures. Evaluated features were grouped into preoperative, pathological and perioperative parameters, which were associated with the ASA system by statistical methods. RESULTS: Overall, the surgical approach was robot assisted (RARP) in 86% of patients and PLND was performed in 65.1% of cases. Any postoperative Clavien-Dindo complication at discharge occurred in 27.2% of cases. The distribution of the ASA physical status system was as follows: ASA I in 108 patients (8.1%), ASA II in 1081 subjects (81.3%) and ASA III in 140 cases (10.5%). Median LOHS was the same for ASA groups I and II (4 days), but longer (5 days) for the ASA group III. There were significant associations of the ASA grading system with physical and perioperative features. As the physical state deteriorated, age, body mass index (BMI), intraoperative blood lost, postoperative Clavien-Dindo complications and length of hospital stay (LOHS). On multivariate Cox proportional hazards, the risk of being free of any postoperative complication at hospital discharge decreased as the ASA physical system deteriorated, as open RP (ORP) was performed as well as intraoperative blood lost increased; furthermore, the strength of associations were stronger for ASA III (hazard ratio, HR=1,659; 95%CI: 1,181 – 2,332; p=0.004) than for ORP and blood lost. CONCLUSIONS: In large contemporary cohort patients undergoing PCa surgery, ASA system associated with any Clavien-Dindo complication at hospital discharge as well as with LOHS. As the physical system of patients deteriorated, the risk of being free from any postoperative complication decreased and LOHS delayed, as well. Although PCa surgery is a hazard in ASA III subgroup, RP can be safely delivered in tertiary referral centers. ASA physical status grading system, together with age and life expectancy, is an important parameter for counselling PCa patients. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e1112-e1112 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Riccardo Rizzetto More articles by this author Antonio Benito Porcaro More articles by this author Nelia Amigoni More articles by this author Alessandro Tafuri More articles by this author Clara Cerrato More articles by this author Alberto Bianchi More articles by this author Sebastian Gallina More articles by this author Rossella Orlando More articles by this author Alessandra Gozzo More articles by this author Filippo Milgliorini More articles by this author Stefano Zecchini Antoniolli More articles by this author Carmelo Monaco More articles by this author Vincenzo De Marco More articles by this author Matteo Brunelli More articles by this author Maria Angela Cerruto More articles by this author Enrico Polati More articles by this author Alessandro Antonelli More articles by this author Expand All Advertisement Loading ...