MP63-08 DETRUSOR CONTRACTION DURATION IN MEN: DESCRIPTION AND CLINICAL CORRELATES

Abstract

You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Non-neurogenic Voiding Dysfunction II (MP63)1 Sep 2021MP63-08 DETRUSOR CONTRACTION DURATION IN MEN: DESCRIPTION AND CLINICAL CORRELATES Albert Ha, Jenny Nguyen, Sheng Chow, and Doreen Chung Albert HaAlbert Ha More articles by this author , Jenny NguyenJenny Nguyen More articles by this author , Sheng ChowSheng Chow More articles by this author , and Doreen ChungDoreen Chung More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002103.08AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Little is known about detrusor contraction duration (DCD) in urodynamic studies (UDS). Our aim was to identify patient characteristics, symptoms and urodynamic parameters associated with DCD in men. METHODS: A retrospective database of UDS (2015-2019) was queried, and 78 male patients with measurable voluntary DCD were identified. Baseline patient characteristics, presenting symptoms and urodynamic parameters were analyzed. Bladder Outlet Obstruction Index (BOOI) and Bladder Contractility Index (BCI) were also calculated using the modified Abrams-Griffiths and Schaefer nomograms, respectively. Wilcoxon Rank-Sum Tests were used for descriptive statistics, and a univariable generalized linear model conforming to a gamma distribution was used to analyze the outcome of DCD. RESULTS: Median age was 70 years (IQR 59-78), BMI was 26.5 kg/m2 (IQR 23.2-30.4), and DCD was 116 seconds (IQR 74.5-169). On univariable regression analysis (Table 1), neurogenic bladder (β=-53.85, 95% CI [-80.75, -20.89], p<0.001), pelvic radiation (β=-49.96, 95% CI [-76.41, -17.38], p<0.001), and stress incontinence (β=-36.24, 95% CI [-63.73, -4.02], p=0.02) were significantly associated with reduced DCD. In contrast, nocturia was significant with a longer DCD (β=41.36, 95% CI [12.44, 69.83], p=0.01). Further analysis revealed that DCD was significantly increased per unit increase of Pdet at Qmax (β=1.51, 95% CI [0.85, 2.2] , p<0.001), maximum Pdet (β=2.13, 95% CI [1.84, 2.42], p<0.001), voided volume (β=0.13, 95% CI [0.04, 0.25], p=0.01), and obstruction by the BOOI (β=51.74, 95% CI [17.57, 90.86], p=0.01). No significant associations were identified in compliance, Qmax, or BCI with DCD. CONCLUSIONS: Obstructed voiding and nocturia appear to be associated with increased DCD, whereas stress incontinence, neurogenic bladder and pelvic radiation are associated with decreased DCD. Moreover, voided volume, Pdet at Qmax, or maximum Pdet appear to affect DCD, while bladder compliance and Qmax do not. Further studies are needed to evaluate the predictive value of these findings. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e1104-e1104 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Albert Ha More articles by this author Jenny Nguyen More articles by this author Sheng Chow More articles by this author Doreen Chung More articles by this author Expand All Advertisement Loading ...