MP61-15 PREDICTING RENAL FUNCTIONAL OUTCOMES AFTER PARTIAL NEPHRECTOMY: A COMPARISON OF NEPHROMETRY SYSTEMS

Abstract

You have accessJournal of UrologyKidney Cancer: Epidemiology & Evaluation/Staging/Surveillance III (MP61)1 Sep 2021MP61-15 PREDICTING RENAL FUNCTIONAL OUTCOMES AFTER PARTIAL NEPHRECTOMY: A COMPARISON OF NEPHROMETRY SYSTEMS Jillian Egan, Sandeep Gurram, Jeunice Owens-Walton, Winston Li, Alexis Rompre-Brodeur, Michael Ahdoot, Nitin Yerram, Patrick Gomella, Heather Chalfin, W. Marston Linehan, and Mark W. Ball Jillian EganJillian Egan More articles by this author , Sandeep GurramSandeep Gurram More articles by this author , Jeunice Owens-WaltonJeunice Owens-Walton More articles by this author , Winston LiWinston Li More articles by this author , Alexis Rompre-BrodeurAlexis Rompre-Brodeur More articles by this author , Michael AhdootMichael Ahdoot More articles by this author , Nitin YerramNitin Yerram More articles by this author , Patrick GomellaPatrick Gomella More articles by this author , Heather ChalfinHeather Chalfin More articles by this author , W. Marston LinehanW. Marston Linehan More articles by this author , and Mark W. BallMark W. Ball More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002101.15AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Various nephrometry systems (NS) have been created to predict perioperative outcomes following nephron-sparing surgery (NSS). The aim of this study was to examine RENAL, PADUA, centrality index (C-index) and contact surface area (CSA) scores and their association with renal functional outcomes (RFO) after partial nephrectomy (PN). METHODS: An IRB-approved, prospectively maintained registry was queried for patients who underwent PN for a single renal mass from 2008-2019 and had 12-month (mo) postoperative renal function follow-up. Computerized tomography or magnetic resonance imaging was reviewed to obtain RENAL, PADUA, C-index and CSA for each patient. Postoperative renal function was measured by serum creatinine and estimated glomerular filtration rate (eGFR) or by 99-mTC-mercaptoacetyltriglycine renogram (MAG3). Correlations between NS and RFO were analyzed to determine their predictive capabilities. RESULTS: 122 patients underwent PN; 13 (10.5%), 73 (60%), 36 (29.5%) were under cold, warm, and no ischemia, respectively. 72 of these patients had postoperative MAG3 scan. Median age was 48 years [Interquartile range (IQR) 38-56]. Median tumor size was 3.2 cm [IQR 2.6-4.5]. Median baseline GFR was 84 ml/min [IQR 72-102 ml/min]. Median percent decrease in 12 mo GFR was 4.3% [IQR -6.8-14.7%]. On univariate analysis, only high PADUA class was associated with percent decrease in 12 mo GFR (13.2%, p=0.012). High RENAL class and CSA were associated with postoperative renal function changes detected by MAG3 (10.5%, p =0.002 and 0.10%, p=0.004). On multivariate analysis, only high PADUA class was associated with percent decrease in 12-mo GFR (11.7%, p=0.03) when controlling for EBL, baseline GFR, and ischemia type (warm vs. cold vs. no ischemia). CONCLUSIONS: This study demonstrates the variability in the ability of different NS to predict long-term RFO. PADUA NS appears to be most predictive of postoperative renal function following PN. Further study is needed to determine association of NS with other perioperative outcomes. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e1088-e1089 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Jillian Egan More articles by this author Sandeep Gurram More articles by this author Jeunice Owens-Walton More articles by this author Winston Li More articles by this author Alexis Rompre-Brodeur More articles by this author Michael Ahdoot More articles by this author Nitin Yerram More articles by this author Patrick Gomella More articles by this author Heather Chalfin More articles by this author W. Marston Linehan More articles by this author Mark W. Ball More articles by this author Expand All Advertisement Loading ...