MP59-07 LONG TERM COMPARATIVE OUTCOMES OF ROBOTIC PARTIAL NEPHRECTOMY AND CRYOABLATION IN PATIENTS WITH SOLITARY KIDNEYS: A SINGLE CENTER ANALYSIS

Abstract

You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy V (MP59)1 Sep 2021MP59-07 LONG TERM COMPARATIVE OUTCOMES OF ROBOTIC PARTIAL NEPHRECTOMY AND CRYOABLATION IN PATIENTS WITH SOLITARY KIDNEYS: A SINGLE CENTER ANALYSIS Alp Tuna Beksac, Dillon Corrigan, Mahmoud Abou Zeinab, Zeyad Schwen, Alireza Aminsharifi, and Jihad Kaouk Alp Tuna BeksacAlp Tuna Beksac More articles by this author , Dillon CorriganDillon Corrigan More articles by this author , Mahmoud Abou ZeinabMahmoud Abou Zeinab More articles by this author , Zeyad SchwenZeyad Schwen More articles by this author , Alireza AminsharifiAlireza Aminsharifi More articles by this author , and Jihad KaoukJihad Kaouk More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002094.07AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Patients with solitary kidneys are sensitive to postoperative acute kidney injury (AKI) following partial nephrectomy (PN). Cryoablation (CA) is a viable alternative to partial nephrectomy (PN) in treating small renal masses of patients with solitary kidneys. In this study, we compared the functional and oncological outcomes of CA and PN in patients with solitary kidney. METHODS: From a single institution, 74 patients with a solitary kidney who underwent small renal mass treatment were selected. 31 patients underwent PN and 43 patients underwent CA. Functional and oncological outcomes were compared between the two groups, with a median follow up of 59.4 months. AKI is defined according to RIFLE (Risk, Injury, and Failure; and Loss; and End-stage kidney disease) criteria. Linear and logistic regression models were used for functional outcomes analysis, whereas oncological outcomes were analyzed using the Kaplan-Meier method. RESULTS: At baseline, the PN group had lower median age (59 years vs 68, p<0.001) and larger median tumor size (2.80 cm vs 2.0, p=0.003). AKI at discharge was more common in the PN group (58% vs 2.8%, p<0.001). eGFR preservation at discharge was higher in the CA group (100% vs 71%, p<0.001). However, eGFR preservation was similar at one year (92% vs. 88.7%, p=0.177) and last follow up (84% vs. 83%, p=0.443). Recurrence rate was higher in the CA group (26.3% vs 3.2%, p=0.009). Majority of recurrences were treated with repeat ablation (55.4%). Lower recurrence free survival (RFS) rate was seen in the CA group (p=0.027), however, overall survival (OS) was comparable between the two groups (p=0.16). CONCLUSIONS: CA is shown to decrease the transient AKI in the immediate outcome compared to PN. However, long term functional outcome is similar. Oncologically, CA has significantly higher recurrence rate and repeat treatment rate. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e1032-e1032 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Alp Tuna Beksac More articles by this author Dillon Corrigan More articles by this author Mahmoud Abou Zeinab More articles by this author Zeyad Schwen More articles by this author Alireza Aminsharifi More articles by this author Jihad Kaouk More articles by this author Expand All Advertisement Loading ...