MP59-03 THULIUM LASER ENUCLEATION (ThuLEP) VERSUS TRANSURETHRAL BIPOLAR PROSTATE RESECTION (TURP): PROSPECTIVE RANDOMIZED STUDY: EARLY INTRA- AND POSTOPERATIVE RESULTS

Abstract

You have accessJournal of UrologyCME1 Apr 2023MP59-03 THULIUM LASER ENUCLEATION (ThuLEP) VERSUS TRANSURETHRAL BIPOLAR PROSTATE RESECTION (TURP): PROSPECTIVE RANDOMIZED STUDY: EARLY INTRA- AND POSTOPERATIVE RESULTS Matteo Zanoni, Giuseppe Chiarelli, Paola Arena, Edoardo Beatrici, Maria Chiara Clementi, Cinzia Mazzieri, Paolo Vota, Giovanni Lughezzani, Nicolò Buffi, Milan, Gianluigi Taverna, and Castellanza Matteo ZanoniMatteo Zanoni More articles by this author , Giuseppe ChiarelliGiuseppe Chiarelli More articles by this author , Paola ArenaPaola Arena More articles by this author , Edoardo BeatriciEdoardo Beatrici More articles by this author , Maria Chiara ClementiMaria Chiara Clementi More articles by this author , Cinzia MazzieriCinzia Mazzieri More articles by this author , Paolo VotaPaolo Vota More articles by this author , Giovanni LughezzaniGiovanni Lughezzani More articles by this author , Nicolò BuffiNicolò Buffi More articles by this author , Milan Milan More articles by this author , Gianluigi TavernaGianluigi Taverna More articles by this author , and Castellanza Castellanza More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003312.03AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The aim is the comparison of early intra- and postoperative clinical results between transurethral enucleation of the prostate with thulium laser (ThuLEP) and transurethral bipolar resection of the prostate (TURP) for the treatment of benign prostatic hyperplasia (BPH) in a prospective randomized trial. METHODS: In the study 650 consecutive patients with BPH were randomized: ThuLEP (n=350) and TURP (n=300). The parameters evaluated were: blood loss, catheterisation time, irrigation volume, hospital stay and operating time. At 6 months after surgery they were evaluated: International Prostate Symptom Score (IPSS), maximum flow (Qmax) and postmintional residue (RPM). RESULTS: Patients in each study arm did not show any significant differences in preoperative parameters compared to TURP, ThuLEP required the same operating time (53.69±31.44 vs 61.66±18.7 minutes, p=.123) but resulted in a reduction in lower hemoglobin values (0.45 vs 2.83 g/dL, p=0.005). ThuLEP also determined less non statistically significant catheterisation time, lower irrigation volume (29.4 vs 69.2 L, p=0.002) and lower non-significant hospital stay (1.7 vs 2.5 days). During the 6-month follow-up, procedures did not show a significant difference in Qmax, IPSS, PVR and Quality of life Scale (QOLS). CONCLUSIONS: ThuLEP and TURP reduce both symptoms of the lower urinary tract with efficacy and safety. ThuLEP is statistically superior to TURP in terms of blood loss, irrigation volume. However, procedures do not differ significantly in Qmax, IPSS, RPM and QOLS for up to 6 months of follow-up. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e806 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Matteo Zanoni More articles by this author Giuseppe Chiarelli More articles by this author Paola Arena More articles by this author Edoardo Beatrici More articles by this author Maria Chiara Clementi More articles by this author Cinzia Mazzieri More articles by this author Paolo Vota More articles by this author Giovanni Lughezzani More articles by this author Nicolò Buffi More articles by this author Milan More articles by this author Gianluigi Taverna More articles by this author Castellanza More articles by this author Expand All Advertisement PDF downloadLoading ...