MP58-03 LONGITUDINAL CHANGES IN THE “PELVIC PAIN ONLY” and “WIDESPEAD PAIN” PHENOTYPES IN IHE MAPP UROLOGIC CHRONIC PELVIC PAIN SYNDOME (UCPPS) COHORT

Abstract

You have accessJournal of UrologyInfections/Inflammation/Cystic Disease of the Genitourinary Tract: Prostate & Genitalia (MP58)1 Apr 2020MP58-03 LONGITUDINAL CHANGES IN THE “PELVIC PAIN ONLY” and “WIDESPEAD PAIN” PHENOTYPES IN IHE MAPP UROLOGIC CHRONIC PELVIC PAIN SYNDOME (UCPPS) COHORT H. Henry Lai*, Emine Bayman, J. Richard Landis, Steven Harte, J. Quentin Clemens, Larissa Rodriguez, Siobhan Sutcliffe, Bayley Taple, and Bruce Naliboff H. Henry Lai*H. Henry Lai* More articles by this author , Emine BaymanEmine Bayman More articles by this author , J. Richard LandisJ. Richard Landis More articles by this author , Steven HarteSteven Harte More articles by this author , J. Quentin ClemensJ. Quentin Clemens More articles by this author , Larissa RodriguezLarissa Rodriguez More articles by this author , Siobhan SutcliffeSiobhan Sutcliffe More articles by this author , Bayley TapleBayley Taple More articles by this author , and Bruce NaliboffBruce Naliboff More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000927.03AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Urologic chronic pelvic pain syndrome (UCPPS) is a heterogeneous syndrome with a variety of potential clinical phenotypes and diverse etiologies. Previous work from the MAPP Research Network identified several pain phenotypes within UCPPS based on the distribution of pain across the body: 1) “Pelvic Pain Only”, 2) “Widespread Pain”, and 3) an “Intermediate” group.1 Here we examined longitudinal changes in body pain phenotypes, focusing on how often patients progressed from “Pelvic Pain Only” at baseline to “Widespread Pain” at follow ups; and conversely, how often “Widespread Pain” changed to “Pelvic Pain Only” over time. METHODS: Men and women with UCPPS (IC/BPS or CP/CPPS) who enrolled in the MAPP-I Epidemiology and Phenotyping Study completed a self-report whole body map to indicate the locations of pain every 2 months for 12 months (at baseline, and during 2, 4, 6, 8, 10, 12-month follow ups). Patients were categorized at each assessment into one of three pain phenotypes: 1) “Pelvic Pain Only” if pain was restricted to the pelvic region only, 2) “Widespread Pain” if 3 or more body regions had pain, and 3) an “Intermediate” group if 1-2 body regions had pain.1 Only patients who completed 3 or more follow-ups were included in this longitudinal analysis. The primary outcome measure was the group classification for the majority of follow up assessments. To be included in a group, patients had to qualify for the same group at ≥60% of the follow-up visits. RESULTS: Among the 93 UCPPS patients with “Pelvic Pain Only” at baseline, only 2 patients (2%) showed a “Widespread Pain” phenotype at the majority of assessments over 12 months of follow up. Among the 121 patients who had “Widespread Pain” at baseline, 7 patients (6%) demonstrated “Pelvic Pain Only” at the majority of assessments over 12 months of follow up. Figure 1 shows the frequency of majority phenotypes during 12 months of follow up for each phenotype at baseline. CONCLUSIONS: It was uncommon for UCPPS patients to change phenotypes from “Pelvic Pain Only” to “Widespread Pain” or vice versa over 12 months. Although patients endorsed fluctuations in number of pain regions, their phenotypic membership remained relatively stable over time. Source of Funding: NIH/NIDDK © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e871-e872 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information H. Henry Lai* More articles by this author Emine Bayman More articles by this author J. Richard Landis More articles by this author Steven Harte More articles by this author J. Quentin Clemens More articles by this author Larissa Rodriguez More articles by this author Siobhan Sutcliffe More articles by this author Bayley Taple More articles by this author Bruce Naliboff More articles by this author Expand All Advertisement PDF downloadLoading ...