MP57-14 DOES DEHYDRATED AMNIOTIC/CHORION HUMAN MEMBRANE (DACHM), ACCELERATES THE RETURN TO POTENCY FOLLOWING ROBOT-ASSISTED RADICAL PROSTATECTOMY REGARDLESS THE DEGREE OF NERVE SPARING?: PROPENSITY SCORE-MATCHED ANALYSIS

Abstract

RESULTS: We identified 22,802 patients that met the inclusion criteria for undergoing malignancy-related prostatectomy. Based on reported smoking history, 2,799 (12.3%) were identified to be current smokers, 2,557 (8.2%) were former smokers, and 17,446 (79.5%) were never smokers. Current smokers were found to have a higher rate of total complications (5.7%) in comparison to former (4.8%) and never smokers (4.6%; P 1⁄4 0.050). Notably, post-operational pneumonia was more frequent in current smokers (0.4%) when compared to former smokers (0.2%) and never smokers (0.2%; P1⁄4 0.039). Unplanned intubation was also found to occur more frequently in current smokers (0.4%) when compared to former smokers (0.3%) and never smokers (0.1%; P 1⁄4 0.002). Multivariate analysis that included smoking status, demographic factors, and preoperative comorbidities found that current smoking status wasan independent predictor of increased risk of total complications (OR, 1.27 [95% CI, 1.06 to 1.53]; P 1⁄4 0.011) and occurrence of unplanned intubation (OR, 5.87 [95% CI, 2.18 to 15.8]; P < 0.001). CONCLUSIONS: In those undergoing prostatectomy, current smoking status influences the risk postoperative complications. Moreover, smoking within the year prior to surgery is an independent predictor of total complications and unplanned intubation within 30 days of the procedure.