MP57-12 PATIENT REPORTED SEXUAL AND URINARY FUNCTIONAL OUTCOMES IN MEN WITH INTERMEDIATE RISK PROSTATE CANCER UNDERGOING RADICAL PROSTATECTOMY: ANALYSIS OF THE MUSIC REGISTRY

Abstract

You have accessJournal of UrologyCME1 May 2022MP57-12 PATIENT REPORTED SEXUAL AND URINARY FUNCTIONAL OUTCOMES IN MEN WITH INTERMEDIATE RISK PROSTATE CANCER UNDERGOING RADICAL PROSTATECTOMY: ANALYSIS OF THE MUSIC REGISTRY Roshan Paudel, John Cochrane, Ji Qi, Michael Cher, Richard Sarle, James Peabody, S. Mohammad Jafri, Brian Lane, Alice Semerjian, Arvin George, and Kevin Ginsburg Roshan PaudelRoshan Paudel More articles by this author , John CochraneJohn Cochrane More articles by this author , Ji QiJi Qi More articles by this author , Michael CherMichael Cher More articles by this author , Richard SarleRichard Sarle More articles by this author , James PeabodyJames Peabody More articles by this author , S. Mohammad JafriS. Mohammad Jafri More articles by this author , Brian LaneBrian Lane More articles by this author , Alice SemerjianAlice Semerjian More articles by this author , Arvin GeorgeArvin George More articles by this author , and Kevin GinsburgKevin Ginsburg More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002640.12AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To assess patient reported continence and sexual function outcomes among men with intermediate risk prostate cancer (IRPC) undergoing radical prostatectomy (RP) in MUSIC. METHODS: We reviewed the Patient Reported Outcome program in the MUSIC prostate cancer registry for men with IRPC undergoing RP from May 2014-- to June 2021. EPIC-26 surveys are administered at baseline and 1, 3, 6, 12, and 24 month postoperatively. To quantify deterioration in function resulting from surgery, patients were included in this analysis if they report good urinary and/or sexual function at baseline. Social continence (SC) was defined as self-reported use of 0-1 pad per day and assessed at 3 and 6 months postoperatively. Good sexual function (SF) was defined as erections firm enough for penetration and assessed at 12 and 24 months postoperatively. Proportions of patients with social continence and good sexual function were compared between favorable (F-IRPC) and unfavorable (U-IRPC) with the Chi-squared test. Surgeon level variation was assessed graphically. RESULTS: Among 3967 patients undergoing RP for IRPC, 2911 and 2614 patients with good baseline urinary function completed the 3m and 6m surveys and 984 and 666 patients with good baseline sexual function completed the 12m and 24m surveys. Post-operative SC was reported in 67% and 86% of patients at 3m and 6m. We noted similar SC for men with F-IRPC and U-IRPC at 3m (68% vs. 67%, p=0.61) and 6m (86% vs. 85%, p=0.74) postoperatively. Recovery of SF was less robust, with 26% and 30% of men reporting good SF at 12m and 24m postoperatively. Men with F-IRPC had improved SF at 12m compared with men with U-IRPC (30% vs. 24%, p=0.031), although this difference was not statistically significant at 24m (34% vs. 28%, p=0.064). There was notable variability in recovery of SC and SF by contributing surgeon for both men with F-IRPC and U-IRPC (Figure). CONCLUSIONS: As reported in MUSIC PRO, men with IRPC had reasonable urinary continence recovery postoperatively overall, but generally poor recovery of erectile function, with notable variation in postoperative urinary and sexual function by surgeon. These data may inform patients and surgeons regarding the range of expected outcomes as well as drive future quality improvement efforts. Source of Funding: Funding from Blue Cross Blue Shield of Michigan © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e986 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Roshan Paudel More articles by this author John Cochrane More articles by this author Ji Qi More articles by this author Michael Cher More articles by this author Richard Sarle More articles by this author James Peabody More articles by this author S. Mohammad Jafri More articles by this author Brian Lane More articles by this author Alice Semerjian More articles by this author Arvin George More articles by this author Kevin Ginsburg More articles by this author Expand All Advertisement PDF DownloadLoading ...