MP57-07 PENILE PROSTHESIS COMPLICATIONS – ARE THEY MORE COMMON AFTER CYSTECTOMY? A MATCHED-COHORT ANALYSIS

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Surgical Therapy (MP57)1 Sep 2021MP57-07 PENILE PROSTHESIS COMPLICATIONS – ARE THEY MORE COMMON AFTER CYSTECTOMY? A MATCHED-COHORT ANALYSIS Carlos Munoz-Lopez, Kevin Lewis, Molly Dewitt-Foy, Zaeem Lone, Drogo Montague, Kenneth Angermeier, and Bradley Gill Carlos Munoz-LopezCarlos Munoz-Lopez More articles by this author , Kevin LewisKevin Lewis More articles by this author , Molly Dewitt-FoyMolly Dewitt-Foy More articles by this author , Zaeem LoneZaeem Lone More articles by this author , Drogo MontagueDrogo Montague More articles by this author , Kenneth AngermeierKenneth Angermeier More articles by this author , and Bradley GillBradley Gill More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002087.07AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Evaluate whether inflatable penile prosthesis (IPP) after radical cystectomy (RC) is associated with higher complication rates compared to IPP for other etiologies of erectile dysfunction (ED). METHODS: All IPPs within the past 20 years in a large regional health system were reviewed and ED etiology determined: RC, radical prostatectomy (RP), or organic/other ED (OED). Cohorts were generated by 1:3 propensity score match using age, body mass index, and diabetes status. Baseline demographics and relevant comorbidities were assessed. Clavien-Dindo complications and grade, as well as reoperation were assessed. Multivariable logarithmic regression with relevant variables identified predictors of 90-day complications. Kaplan-Meier analysis assessed time to reoperation after RC compared to other ED etiologies. RESULTS: Of 2600 patients identified, 231 matched for analyses. Demographic characteristics did not differ. Implantation of 3-piece devices was less common after RC (RC:64% vs. RP:90% vs. OED:94%, p <0.001), whereas ectopic reservoir placement was more common (RC:100% vs. RP:61% vs. OED:3%, p <0.001). Comparing RC vs pooled Non-RC indications, RC had a 4-fold greater complication rate (12% vs 3%, p=0.04) whereas complication rates did not significantly differ across specific ED etiologies (RC: 24% vs. RP: 8% vs. OED: 10%, p=0.06). Clavien-Dindo complication grades did not differ across groups. Regression showed 2-piece systems independently ‘protected’ against complication (OR: 0.3, p=0.03). Reoperation was significantly more common with RC (RC: 21% vs. non-RC: 7%, p=0.014) but time to reoperation did not differ by IPP indication (p=0.088). CONCLUSIONS: IPP is a valid option for radical cystectomy patients who historically benefitted from 2-piece systems, however contemporary low-profile reservoirs may expand the benefit of 3-piece devices to this patient population. Source of Funding: N/A © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e980-e981 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Carlos Munoz-Lopez More articles by this author Kevin Lewis More articles by this author Molly Dewitt-Foy More articles by this author Zaeem Lone More articles by this author Drogo Montague More articles by this author Kenneth Angermeier More articles by this author Bradley Gill More articles by this author Expand All Advertisement Loading ...