Abstract
You have accessJournal of UrologyProstate Cancer: Staging I1 Apr 2018MP53-13 IS THE CANCER OF THE PROSTATE RISK ASSESSMENT SCORE A VALID TOOL TO PREDICT BIOCHEMICAL RECURRENCE, METASTASIS AND DEATH AFTER RADICAL PROSTATECTOMY IN LATIN AMERICAN PATIENTS? Rubén Bengió, leandro Arribillaga, Hernán García Onto, Javier Epelde, Esteban Cordero, Verónica Bengió, and Ruben. H Bengió Rubén BengióRubén Bengió More articles by this author , leandro Arribillagaleandro Arribillaga More articles by this author , Hernán García OntoHernán García Onto More articles by this author , Javier EpeldeJavier Epelde More articles by this author , Esteban CorderoEsteban Cordero More articles by this author , Verónica BengióVerónica Bengió More articles by this author , and Ruben. H BengióRuben. H Bengió More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.1684AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Radical prostatectomy is an effective modality of treatment of localized prostate cancer at all levels of risk. However, the recurrence of the disease has been described in more than 40% of the patients after radical prostatectomy. Therefore, to determine the risk of disease and thus trying to Stratify it is essential in these tumors. Thus, various tools for predicting postoperative evolution have been developed and subsequently validated in several studies. In 2011, the University of California, San Francisco proposed the Cancer of the Prostate Risk Assessment Score (CAPRA-S), which uses clinical and pathological information in order to predict progression of an easy and reasonable way. The aim of the present study is to perform external validation to determine whether the Cancer of the Prostate Risk Assessment score (CAPRA-S) predicts biochemical recurrence, metastasis and death for prostate cancer after radical prostatectomy in Latin American population. METHODS 216 patients were studied. Probability of score to predict biochemical recurrence after radical prostatectomy was analyzed by Cox proportional method. Biochemical recurrence, metastasis and cancer specific free survival was determinate by Kaplan method. Exactitude of CAPRA-S score to predict biochemical recurrence, metastasis and death by prostate cancer was made in accordance with Harrells concordance index. RESULTS median follow up was 74 months. Biochemical recurrence index increase proportionally with the increment of CAPRA-S score. In the stratification of patients in low, intermediate or high risk, biochemical recurrence free rate were 85%, 54% and 4% respectively. Concordance index (C-Index) to biochemical progression, metastasis and death by prostate cance were 0.85, 0.90 and 0.90 respectively. CONCLUSIONS CAPRA-S score is an easily applicable tool and had high predictive exactitude to determinate biochemical recurrence, metastasis and death by prostate cancer in our population. Concordance Index in these variables was higher than 0.85. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e708-e709 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Rubén Bengió More articles by this author leandro Arribillaga More articles by this author Hernán García Onto More articles by this author Javier Epelde More articles by this author Esteban Cordero More articles by this author Verónica Bengió More articles by this author Ruben. H Bengió More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.