Abstract
You have accessJournal of UrologySexual Function/Dysfunction: Evaluation1 Apr 2016MP47-09 COLOR DOPPLER DUPLEX ULTRASOUND (CDDU) PARAMETERS OF MEN WITHOUT ORGANIC ERECTILE DYSFUNCTION Ram Pathak, Andrew Davidiuk, Issac Effriong, Zhuo Li, and Gregory Broderick Ram PathakRam Pathak More articles by this author , Andrew DavidiukAndrew Davidiuk More articles by this author , Issac EffriongIssac Effriong More articles by this author , Zhuo LiZhuo Li More articles by this author , and Gregory BroderickGregory Broderick More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.328AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Erectile Dysfunction (ED) can be non-invasively diagnosed by Color Duplex Doppler Ultrasound (CDDU) coupled with intracavernous injection (ICI) of a penile vasoactive agent. The primary aim of the study was to construct age-specific CDDU parameters for patients without organic erectile dysfunction. METHODS A retrospective review was conducted to identify patients without organic ED who underwent in-office testing with intracavernous pharmacologic erection augmented by visual sexual stimulation and CDDU over a 5 year period. Patients were further characterized by demographic and Doppler data. Specifically, CDDU characteristics including pre and post-visual stimulation peak systolic velocity (PSV) and resistive index (RI) were identified. Patients with post-visual stimulation PSV > 35cm/s and RI > 0.9 were included in the analysis. Pearson correlation test was used to evaluate the association between ordinal age groups with PSV and RI measurements. RESULTS 259 patients with a mean age 53.7 and a mean BMI of 27.2 were found to have normal Doppler parameters (PSV>35cm/s, RI>.90). For the entire cohort, average post-visual stimulation PSV was 59.8 (35.0-115.5) and average RI was 0.99 (.9-1.0). A majority of patients had limited medical co-morbidities, with only 29%, 7%, and 10% reporting hypertension, Diabetes, and heart disease, respectively. Priapism, as defined by needing an injectable reversible agent, occurred in 93% of patients. Doppler parameters were then analyzed across sequential decades and when age was categorized to <30, 30-39, 40-49, 50-59, 60-69, and >70, a negative correlation coefficient was obtained for pre-visual stimulation PSV (-0.09, P=0.164), post-visual stimulation PSV (-0.23, P=0.005) and RI (-0.005, P=.937). Pre-visual stimulation, post-visual stimulation and RI were also stratified using age as continuous variable and with a cutoff of age = 60 (Table 1). CONCLUSIONS No patients were diagnosed with arterial insufficiency or cavernous venous occlusive disease. There appears to be an age-related decline in post-visual stimulation PSV. Characterization of Doppler parameters in patients without organic ED can be used to construct cutoffs to further define age-specific normalcy. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e629-e630 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Ram Pathak More articles by this author Andrew Davidiuk More articles by this author Issac Effriong More articles by this author Zhuo Li More articles by this author Gregory Broderick More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
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