MP47-03 ERECTILE FUNCTION AFTER LOW DOSE-RATE PROSTATE BRACHYTHERAPY - LONG TERM FOLLOW-UP FOR 3 YEARS

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Evaluation1 Apr 2016MP47-03 ERECTILE FUNCTION AFTER LOW DOSE-RATE PROSTATE BRACHYTHERAPY - LONG TERM FOLLOW-UP FOR 3 YEARS Andreas Bannowsky, Leif Bäurle, Stefan Ückert, Tillmann Loch, and Hermann van Ahlen Andreas BannowskyAndreas Bannowsky More articles by this author , Leif BäurleLeif Bäurle More articles by this author , Stefan ÜckertStefan Ückert More articles by this author , Tillmann LochTillmann Loch More articles by this author , and Hermann van AhlenHermann van Ahlen More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.322AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To evaluate the effect of low-dose rate prostate (LDR) brachytherapy on erectile function in correlation to the time intervals after seed implantation. METHODS 32 patients with localized prostate cancer and a median age of 74 years (range 65-83) were treated with permanent seed implantation for LDR-brachytherapy. Erectile function was assessed by means of a validated questionnaire (IIEF-5) before and at 12, 24 and 36 months after treatment. No patient received supplemental external beam radiation therapy or antiandrogen therapy. Of the 32 patients, 26 (81%) completed and returned the questionnaire. None of the patients used PDE-5 Inhibitors or intracavernousal injection therapy. RESULTS Before treatment, 15 patients (58%) had no erectile dysfunction (ED) (score 22-25) or mild ED (score 17-21), 11 (42%) mild to moderate or severe ED (score 0-16). Overall, before seed implantation the mean IIEF score was 14.4. The mean IIEF score decreased by 4.4 points 12 months after treatment, 3.1 points 24 months after treatment and 9.8 points 36 months after treatment (p<0.05). In the group of no or mild ED, the mean IIEF score dropped by 9.7 points compared to a decrease of 1.4 points in the group of mild to moderate or severe ED. CONCLUSIONS Most of the patients treated with LDR-brachytherapy suffered an ED in correlation to the time interval with a significant loss in the third year after treatment. In this study, the most significant loss occured in the groups which had no or only mild erectile dysfunction before treatment. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e627 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Andreas Bannowsky More articles by this author Leif Bäurle More articles by this author Stefan Ückert More articles by this author Tillmann Loch More articles by this author Hermann van Ahlen More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...