MP45-16 CRYO ONLINE DATA REGISTRY OUTCOMES: MINIMUM FIVE YEAR FOLLOW UP DATA

Abstract

You have accessJournal of UrologyProstate Cancer: Localized III1 Apr 2014MP45-16 CRYO ONLINE DATA REGISTRY OUTCOMES: MINIMUM FIVE YEAR FOLLOW UP DATA David Levy, Christopher Williams, Thomas Polascik, and Stephen Jones David LevyDavid Levy More articles by this author , Christopher WilliamsChristopher Williams More articles by this author , Thomas PolascikThomas Polascik More articles by this author , and Stephen JonesStephen Jones More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.1213AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail Introduction and Objectives We report a comprehensive update of 5 year COLD Registry outcomes for patients undergoing primary whole gland prostate cryoablation. Methods A risk stratified cohort of 1,111 treatment naïve patients who underwent primary whole gland cryoablation was identified. 5 year biochemical progression free Kaplan Meier survival curves were constructed based on Phoenix definition. Results Overall bPFS was: 79.9%, 64.1% and 68.1%, low, intermediate and high risk, respectively, (Figure 1). For 817 (73.5%) patients with nadir PSA < 0.4 ng/ml, bPFS was 91%, 80.5%, and 77.6%, low, intermediate and high risk, respectively. Patients with a nadir PSA > 0.4 ng/ml demonstrated 24-month biochemical progression rates in excess of 34%. Continence was preserved in 93.4% of patients, while 5.9% of patients had retention and 0.5% developed a rectal fistula. Potency data entered into the Registry data base revealed that 35% of patients were potent at 12 months. Conclusions 5 year bPFS following prostate cryoablation is comparable to surgical and radiation outcomes across all risk categories with a lower likelihood of procedure related complications. A nadir PSA > 0.4 ng/ml predicts a high likelihood of biochemical progression and warrants close follow up. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e465 Peer Review Report Advertisement Copyright & Permissions© 2014MetricsAuthor Information David Levy More articles by this author Christopher Williams More articles by this author Thomas Polascik More articles by this author Stephen Jones More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...