MP43-11 GEOGRAPHIC VARIATION OF INFECTIOUS COMPLICATIONS FOLLOWING PROSTATE BIOPSY IN THE UNITED STATES: RESULTS FROM A PRIVATELY INSURED COHORT

Abstract

You have accessJournal of UrologyProstate Cancer: Detection & Screening IV (MP43)1 Sep 2021MP43-11 GEOGRAPHIC VARIATION OF INFECTIOUS COMPLICATIONS FOLLOWING PROSTATE BIOPSY IN THE UNITED STATES: RESULTS FROM A PRIVATELY INSURED COHORT Jeffrey Morrison, Boris Gershman, Badrinath Konety, Peter Clark, Michael Bronsert, Alexander Kutikov, Anessa Sax-Bolder, Miguel Rodriguez-Homs, Granville Lloyd, Rodrigo Rodrigues Pessoa, and Simon Kim Jeffrey MorrisonJeffrey Morrison More articles by this author , Boris GershmanBoris Gershman More articles by this author , Badrinath KonetyBadrinath Konety More articles by this author , Peter ClarkPeter Clark More articles by this author , Michael BronsertMichael Bronsert More articles by this author , Alexander KutikovAlexander Kutikov More articles by this author , Anessa Sax-BolderAnessa Sax-Bolder More articles by this author , Miguel Rodriguez-HomsMiguel Rodriguez-Homs More articles by this author , Granville LloydGranville Lloyd More articles by this author , Rodrigo Rodrigues PessoaRodrigo Rodrigues Pessoa More articles by this author , and Simon KimSimon Kim More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002064.11AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Clinical practice guidelines recommend antibiotic prophylaxis for transrectal prostate biopsy. However, infectious complications following biopsy have been an emerging concern due to the antibiotic resistance and lack of an established surveillance system. National trends and geographic variation for post-biopsy infectious complications remains poorly understood. Herein, we sought to elucidate trends and variation of infectious complications from a national privately insured database. METHODS: Using MarketScan, we identified all men who underwent a transrectal prostate biopsy due to prostate cancer screening from 2010 to 2015. Infectious complications (UTI, prostatitis, sepsis) occurring 30 days after the prostate biopsy from emergency room (ER) visits or hospital admissions constituted the primary outcomes on a national and state level. We analyzed the unadjusted and adjusted rates of infectious complications from ER visits and hospital admission per 100 prostate biopsies. RESULTS: During the study interval, we identified 193,490 patients who underwent a prostate biopsy. The mean age was 57.6 years (SD: 5.0). Overall, national rates of post-biopsy infectious complications for ER visits and hospital admissions were 0.4 and 0.9 per 100 prostate biopsies, respectively. Over time the unadjusted national rates of infectious complications remained similar from 0.4 ER visits per 100 prostate biopsies in 2010 to 0.3 in 2015 (p=0.83), and 0.9 hospital admissions per 100 prostate biopsies in 2010 to 0.8 in 2015 (p=0.58). At a state level, and averaged over the time period 2010 to 2015, the states with the five highest and five lowest rates of ER visits and hospital admission per 100 prostate biopsies are displayed in Table 1. For ER visits, South Dakota was highest (1.71) and New Hampshire was lowest (0.08). For hospital admissions, Alaska was highest (1.74) and Colorado was lowest (0.39). CONCLUSIONS: While ER visits and hospital admissions attributable from infectious complications due to prostate biopsies remain relatively stable, significant variations exist on a state level. Further research is needed to assess the causes for this regional variation for these infectious complications from prostate biopsies. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e785-e786 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Jeffrey Morrison More articles by this author Boris Gershman More articles by this author Badrinath Konety More articles by this author Peter Clark More articles by this author Michael Bronsert More articles by this author Alexander Kutikov More articles by this author Anessa Sax-Bolder More articles by this author Miguel Rodriguez-Homs More articles by this author Granville Lloyd More articles by this author Rodrigo Rodrigues Pessoa More articles by this author Simon Kim More articles by this author Expand All Advertisement Loading ...