MP43-19 SELF-REPORTED EMOTIONAL FUNCTIONING OF MEN UNDERGOING ACTIVE SURVEILLANCE, RADICAL PROSTATECTOMY, OR RADIOTHERAPY IN THE EUPROMS STUDY

Abstract

You have accessJournal of UrologyProstate Cancer: Detection & Screening IV (MP43)1 Sep 2021MP43-19 SELF-REPORTED EMOTIONAL FUNCTIONING OF MEN UNDERGOING ACTIVE SURVEILLANCE, RADICAL PROSTATECTOMY, OR RADIOTHERAPY IN THE EUPROMS STUDY Lionne Venderbos, André Deschamps, Ernst-Günther Carl, John Dowling, Renée Hogenhout, Sebastiaan Remmers, and Monique Roobol Lionne VenderbosLionne Venderbos More articles by this author , André DeschampsAndré Deschamps More articles by this author , Ernst-Günther CarlErnst-Günther Carl More articles by this author , John DowlingJohn Dowling More articles by this author , Renée HogenhoutRenée Hogenhout More articles by this author , Sebastiaan RemmersSebastiaan Remmers More articles by this author , and Monique RoobolMonique Roobol More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002064.19AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Treatment for localized prostate cancer (PCa) is a preference-sensitive decision in which aspects such as post-treatment quality of life (QoL) should be taken into account. Europa Uomo, representing the voice of men with PCa in Europe, initiated the patient-driven Europa Uomo Patient Reported Outcome Study (EUPROMS) to inform their members about QoL post-PCa treatment. Here the self-reported data on emotional functioning are presented for men who underwent active surveillance (AS), radical prostatectomy (RP), or radiotherapy (RT). METHODS: An invitation to complete a cross-sectional online survey was distributed through Europa Uomo’s network to European PCa patients who underwent treatment. The survey included, amongst others, the EORTC-QLQ-C30 to measure cancer-related QoL [Venderbos et al., Eur Urol Focus 2020*]. The EORTC-QLQ-C30 emotional functioning scale scores and the items that comprise the scale are presented. Item proportions of the three treatment groups were compared with the proportion test. RESULTS: A total of 2943 men completed the EUPROMS survey; respondents median age is 71 years (IQR 65-75) and 82% was living with a spouse. A total of 179 (6.1%) men underwent AS, 1101 (37.4%) RP, and 304 (10.3%) RT. The median emotional functioning scale score is 91.7 for AS, RP and RT with some variation in the IQRs. Looking at the single items of the emotional functioning subscale, proportionally there were slightly more men on AS that felt tense ‘quite a bit’ (10.1% vs. 6.5% and 7.9%, χ(2)=3.4, p=0.2), were worried ‘quite a bit’ (15.6% vs. 10.9% and 9.2%, χ(2) = 4.9, p=0.087), felt irritable ‘quite a bit’ (12.3% vs. 7.5% and 6.3%, χ(2) = 6.1, p=0.047), and felt depressed ‘quite a bit’ (12.9% vs. 8.9% and 7.6 %, χ(2) = 4.0, p=0.14). CONCLUSIONS: Overall, data from the patient-initiated EUPROMS study show that in terms of emotional functioning, AS, RP and RT are well-tolerated treatments. On an individual level it will, however, be interesting to try to identify factors that are associated with positive and negative psychological responses to both diagnosis and treatment of localized PCa, to optimize psychological outcomes also for those men that felt ‘quite a bit’ more tense, worried, irritable or depressed. Source of Funding: This work was supported by Bayer, Ipsen and Janssen. The funders did not play any role in the study design, collection, analysis or interpretation of data © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e789-e790 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Lionne Venderbos More articles by this author André Deschamps More articles by this author Ernst-Günther Carl More articles by this author John Dowling More articles by this author Renée Hogenhout More articles by this author Sebastiaan Remmers More articles by this author Monique Roobol More articles by this author Expand All Advertisement Loading ...