MP40-15 ONCOLOGIC OUTCOMES AFTER ROBOTIC-ASSISTED LAPAROSCOPIC VS RETROPUBIC RADICAL PROSTATECTOMY FOR HIGH-RISK PROSTATE CANCER IN KOREAN MEN USING K-CAP REGISTRY

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You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy I1 Apr 2016MP40-15 ONCOLOGIC OUTCOMES AFTER ROBOTIC-ASSISTED LAPAROSCOPIC VS RETROPUBIC RADICAL PROSTATECTOMY FOR HIGH-RISK PROSTATE CANCER IN KOREAN MEN USING K-CAP REGISTRY Se Young Choi, Chunwoo Lee, Jaeyoon Jung, Sangjun Yoo, Dalsan You, In Gab Jeong, Seok-Soo Byun, Ji Youl Lee, Byung Ha Chung, and Chung-Soo Kim Se Young ChoiSe Young Choi More articles by this author , Chunwoo LeeChunwoo Lee More articles by this author , Jaeyoon JungJaeyoon Jung More articles by this author , Sangjun YooSangjun Yoo More articles by this author , Dalsan YouDalsan You More articles by this author , In Gab JeongIn Gab Jeong More articles by this author , Seok-Soo ByunSeok-Soo Byun More articles by this author , Ji Youl LeeJi Youl Lee More articles by this author , Byung Ha ChungByung Ha Chung More articles by this author , and Chung-Soo KimChung-Soo Kim More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.161AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Previous studies have shown that robot-assisted radical prostatectomy (RARP) can be performed in men with high-risk prostate cancer (PCa) with similar outcomes to that of open radical prostatectomy (ORP). However, most of the literature consists of small case series. This study compared a cohort of high-risk patients undergoing open ORP and RARP at three institutions (K-CaP registry). METHODS In total, 3,206 patients with prostate cancer were identified in the multicenter Korean Prostate Cancer Database (K-CaP registry). Overall, 928 patients with high-risk PCa in three institution were underwent surgery. Patients were treated with RARP or ORP. Pathological T stage, positive surgical margins, biochemical recurrence (BCR) and cancer-specific survival (CSS) were compared. Multivariate models were developed to determine whether surgical approach influences BCR and CSS. RESULTS Overall, 295 (31.8%) and 633 (68.2%) patients underwent ORP and RARP, respectively. Mean follow-up was 59 months. No differences after surgery were observed in pathologic N stage and Gleason score between patients treated with RARP and ORP. However, ORP was associated with advanced PCa than RARP in resection margin, pathologic tumor volume, clinical and pathologic T stage (P<0.049). A multivariate Cox proportional hazards model for BCR showed that preoperative PSA (HR=1.007, p=0.010), RALP (vs. ORP, HR=1.115, p=0.057), Gleason score (= 8, HR=3.996, p<0.001) were significant predictors. CONCLUSIONS RALP appears to be a feasible option for men with high-risk prostate cancer and displayed equivalent BCR and CSS compared with ORP. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e556-e557 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Se Young Choi More articles by this author Chunwoo Lee More articles by this author Jaeyoon Jung More articles by this author Sangjun Yoo More articles by this author Dalsan You More articles by this author In Gab Jeong More articles by this author Seok-Soo Byun More articles by this author Ji Youl Lee More articles by this author Byung Ha Chung More articles by this author Chung-Soo Kim More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...