MP37-01 EXPANDED PROSTATE CANCER INDEX COMPOSITE-26 (EPIC-26) ONLINE: VALIDATION OF AN INTERNET-BASED INSTRUMENT FOR ASSESSMENT OF HEALTH-RELATED QUALITY OF LIFE AFTER TREATMENT FOR LOCALIZED PROSTATE CANCER

Abstract

You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Practice Patterns, Quality of Life and Shared Decision Making IV1 Apr 2016MP37-01 EXPANDED PROSTATE CANCER INDEX COMPOSITE-26 (EPIC-26) ONLINE: VALIDATION OF AN INTERNET-BASED INSTRUMENT FOR ASSESSMENT OF HEALTH-RELATED QUALITY OF LIFE AFTER TREATMENT FOR LOCALIZED PROSTATE CANCER David Einstein, Kyle Davis, Catrina Crociani, Dattatraya Patil, Andrew Wagner, Martin Sanda, Peter Chang, and PROST-QA Consortium David EinsteinDavid Einstein More articles by this author , Kyle DavisKyle Davis More articles by this author , Catrina CrocianiCatrina Crociani More articles by this author , Dattatraya PatilDattatraya Patil More articles by this author , Andrew WagnerAndrew Wagner More articles by this author , Martin SandaMartin Sanda More articles by this author , Peter ChangPeter Chang More articles by this author , and PROST-QA ConsortiumPROST-QA Consortium More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1678AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Most men will survive for years after treatment for localized prostate cancer (PCa) and may experience lasting treatment-related toxicities that affect health-related quality of life (HRQoL). The Expanded Prostate Cancer Index Composite (EPIC-26) is a validated instrument that measures HRQoL across 5 PCa-specific domains. Previously, EPIC-26 has been administered via phone in a large multicenter clinical trial. In this study, we tested the validity of an Internet-based version of EPIC-26 in comparison to the phone-based version. METHODS We used the Qualtrics system to develop an Internet-based version of EPIC-26 with the same wording and scale of the validated phone version. We recruited subjects from two prospective longitudinal study cohorts: PROST-QA, which includes men with early-stage PCa undergoing primary radical prostatectomy (RP), brachytherapy, or external-beam radiotherapy, and PROSTQA-RP2, which includes similar men undergoing RP. Subjects completed both internet-based and phone-based surveys and were randomized to either an “Internet-first” or “phone-first” group. Subjects were offered the alternate survey modality two weeks after completing the initial modality. We calculated the intraclass correlation coefficients for each health domain between modalities. RESULTS 181 subjects were offered enrollment and 133 agreed to participate (response rate: 73.4%). 65 subjects were randomized to the “Internet-first” group and 68 subjects to the “phone-first” group. Of these, 37 and 26 subjects respectively completed both survey versions. Test-retest analysis showed significant intra-class correlations (p <0.05) in all 5 domains of EPIC-26: urinary incontinence (r=0.96), urinary irritation (r=0.85), bowel function (r=0.61), sexual function (r=0.94), and hormonal function (r=0.89). There was no effect of ordering. CONCLUSIONS This study demonstrates excellent correlation of responses between Internet-based and phone-based EPIC-26 administration. All domains demonstrated test-retest reliability between modalities, without ordering effect. This validates the use of internet-based EPIC-26 in international registries as part of the International Consortium for Health Outcomes Measurement (ICHOM) effort, and may facilitate its use in clinical practice to improve quality of care. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e497 Advertisement Copyright & Permissions© 2016MetricsAuthor Information David Einstein More articles by this author Kyle Davis More articles by this author Catrina Crociani More articles by this author Dattatraya Patil More articles by this author Andrew Wagner More articles by this author Martin Sanda More articles by this author Peter Chang More articles by this author PROST-QA Consortium More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...