MP36-03 PRESENCE OF URINARY UREAPLASMA UREALYTICUM OR UREAPLASMA PARVUM IS NOT ASSOCIATED WITH THE OCCURRENCE OF CHRONIC PROSTATITIS/CHRONIC PELVIC PAIN SYNDROME

Abstract

You have accessJournal of UrologyInfections/Inflammation/Cystic Disease of the Genitourinary Tract: Prostate & Genitalia II1 Apr 2016MP36-03 PRESENCE OF URINARY UREAPLASMA UREALYTICUM OR UREAPLASMA PARVUM IS NOT ASSOCIATED WITH THE OCCURRENCE OF CHRONIC PROSTATITIS/CHRONIC PELVIC PAIN SYNDROME Yu Seo and Gil Lee Yu SeoYu Seo More articles by this author and Gil LeeGil Lee More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1637AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Ureaplasmas are the smallest human parasites. Its slow growth in infected host cells allow for the possibility of being causal pathogen for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Therefore, we examined the presence of Ureaplasma urealyticum (UU) and Ureaplsma pavum (UP) in 696 urine samples from 669 men who attended a urology outpatient clinic with various reasons by using an automated sequencing method. METHODS 696 urine samples that are nonbacterial (from prostate and urine ordinary cultures) and nongonorrheal and nonchlamydial (based on PCR) were randomly selected from stored samples. Clinical information of individual subject is presented in Table 1. We amplified the UU/UP urease complex components with consensus primers. Finally, we read the genetic sequences and classified between the UU and UP from ureaplasma spp. RESULTS The overall rates of UU and UP were 3.88% (27/696) and 6.46% (45/696), respectively. In univariate analysis, only UU infection significantly increases the likehood of urinary WBC count ≥5 only (odds ratio [OR]; 7.377, 95% confidence interval [CI]: 2.244-24.248, P=0.001) (Table 1). However, the presence of both UU and UP in urine do not increase the risk of having the CP/CPPS symptoms and signs. The mean NIH-CPSI scores in total of pain Items, urinary and quality of life items do not differ among the negative, UU positive, and UP positive groups (Table 2). CONCLUSIONS We find that only UU can induce asymptomatic pyuria. However, the presence of urinary UU or UP is not definitively associated with the occurrence of CP/CPPS. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e489-e490 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Yu Seo More articles by this author Gil Lee More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...