MP35-15 CLINICAL FEATURES OF HYDRONEPHROSIS IN PATIENTS WITH BENIGN PROSTATE HYPERPLASIA AND ACUTE URINARY RETENTION

Abstract

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Epidemiology & Evaluation1 Apr 2016MP35-15 CLINICAL FEATURES OF HYDRONEPHROSIS IN PATIENTS WITH BENIGN PROSTATE HYPERPLASIA AND ACUTE URINARY RETENTION Chin-Heng Lu, Howard Hong-Hao Wu, Yu-Hua Fan, Chih-Chieh Lin, Yi-Hsiu Huang, Tzu-Ping Lin, Hsiao-Jen Chung, Junne-Yih Kuo, William Jhih-Sian Huang, Yen-Hua Chang, Alex Tong-Long Lin, and Kuang-Kuo Chen Chin-Heng LuChin-Heng Lu More articles by this author , Howard Hong-Hao WuHoward Hong-Hao Wu More articles by this author , Yu-Hua FanYu-Hua Fan More articles by this author , Chih-Chieh LinChih-Chieh Lin More articles by this author , Yi-Hsiu HuangYi-Hsiu Huang More articles by this author , Tzu-Ping LinTzu-Ping Lin More articles by this author , Hsiao-Jen ChungHsiao-Jen Chung More articles by this author , Junne-Yih KuoJunne-Yih Kuo More articles by this author , William Jhih-Sian HuangWilliam Jhih-Sian Huang More articles by this author , Yen-Hua ChangYen-Hua Chang More articles by this author , Alex Tong-Long LinAlex Tong-Long Lin More articles by this author , and Kuang-Kuo ChenKuang-Kuo Chen More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1607AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Some benign prostatic hyperplasia (BPH) patients with lower urinary tract symptoms (LUTS) hesitated to receive surgical treatment till acute urinary retention (AUR) occurred. Part of them combined hydronephrosis which induced renal insufficiency. Many studies had analyzed risk factors for predicting acute urinary retention and other associated complications in benign prostatic obstruction (BPO) patients. This study aimed to predict what kind of patients who needed transurethral resection of the prostate (TURP) for AUR tended to accompany with hydronephrosis. METHODS We retrospectively evaluated 91 patients who had benign prostate obstruction (BPO) and received TURP for acute urinary retention from January 2014 to June 2015. Exclusion criteria including the patient had urolithiasis, prostate cancer, bladder cancer or gross hematuria. Parameters of intravesical prostatic protrusion (IPP), bladder wall thickness (BWT), serum PSA, total prostate volume, age, BMI, HTN, DM, CAD, serum creatinine and the results from the pressure-flow study (UFR) and cystometrogram (CMG) results were compared between the hydronephrosis group (n=24) and non-hydronephrosis group (n=67). RESULTS The There were significant differences in BWT (p<0.001), IPP (p<0.001) and Cr (p<0.001) between the hydronephrosis and non-hydronephrosis groups. For BWT, the area under the curve was 0.947 (95% confidence interval, 0.888 to 1.000, P<0.0001) and the cutoff value to indicate hydronephrosis was 0.75 mm with 88.0% sensitivity and 91.9% specificity. The odds ratio was 83.6 (95% confidence interval, 18.403 to 379.774). For IPP, the area under the curve was 1.950 (95% confidence interval, 0.720 to 0.344, P<0.0001) and the cutoff value to indicate hydronephrosis was 1.95 mm with 72.0% sensitivity and 65.6% specificity. The odds ratio was 4.909 (95% confidence interval, 1.781 to 13.533) There were no significant differences in age, BMI, DM, HTN, CAD, pre-TURP, PSA, UFR between the 2 groups. IPP was weakly correlated with total prostate volume (p=0.423). There was no significant differences for a specific type of CMG result but 42.3% AUR patients showed overactivity bladder. CONCLUSIONS Clinical parameters of BWT and IPP were significant risk factors for predicting hydronephrosis in BPO patients. If patients’ BWT exceeding 0.75 cm or IPP exceeding 1.95 cm, they have highly risk for combination of hydronephrosis when AUR occurred. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e486 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Chin-Heng Lu More articles by this author Howard Hong-Hao Wu More articles by this author Yu-Hua Fan More articles by this author Chih-Chieh Lin More articles by this author Yi-Hsiu Huang More articles by this author Tzu-Ping Lin More articles by this author Hsiao-Jen Chung More articles by this author Junne-Yih Kuo More articles by this author William Jhih-Sian Huang More articles by this author Yen-Hua Chang More articles by this author Alex Tong-Long Lin More articles by this author Kuang-Kuo Chen More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...