MP35-16 THE IMPACT OF AGE ON OUTCOMES AFTER BLADDER OUTLET PROCEDURES

Abstract

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Epidemiology & Evaluation1 Apr 2016MP35-16 THE IMPACT OF AGE ON OUTCOMES AFTER BLADDER OUTLET PROCEDURES Marc Colaco, Marcus Fluck, John Danella, and Daniel Rukstalis Marc ColacoMarc Colaco More articles by this author , Marcus FluckMarcus Fluck More articles by this author , John DanellaJohn Danella More articles by this author , and Daniel RukstalisDaniel Rukstalis More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1608AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Bladder outlet obstruction caused by benign prostatic hyperplasia (BPH) is a common problem with significant impact on quality of life. While conventional wisdom is to put off definitive treatment until medical therapy has failed, delaying surgical interventions may risk the patient’s ability to recover lost functionality. The purpose of this study is to examine outcomes in symptom reduction after bladder outlet procedures as a function of age. METHODS An IRB approved retrospective review of a prospective quality improvement database was completed using all surgical cases done for prostatic disorders (cancer or BPH related) at a single institution from 1997 through 2011. All subjects reported IPSS scores prior to treatment as well as at each follow up visit. Subjects were stratified by age then examined for mean change in total IPSS, mean change in percent of IPSS, and percentage decreasing to asymptomatic (defined as IPSS of 5 or less). RESULTS A total of 950 subjects were included in this analysis. OF these subjects 612 underwent radical prostatectomy and 338 patients underwent a BPH procedure. There was a positive linear relationship between improvement in IPSS score post treatment and age F(1,949)=9.6, p=0.002. However, when considering percentage improvement, there was a negative linear relationship between percentage improvement change and age F(1,949)=5.46, p=0.02. The number of patients who became asymptotic after their treatment there also saw a linear relationship with the youngest cohort (age less than 50) achieving complete reduction of symptoms 80% of the time while the oldest cohort (age greater than 70) only achieving complete reduction of symptoms 50% of the time (p=0.012, see graph). CONCLUSIONS While older men gain more total symptom reduction from their bladder outlet procedures, they rarely achieve the same percent reduction or low post treatment symptom levels of younger men. These findings may reflex an intrinsic inability for older men to recover lost bladder function and a subsequent need for earlier interventions. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e486-e487 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Marc Colaco More articles by this author Marcus Fluck More articles by this author John Danella More articles by this author Daniel Rukstalis More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...