Abstract

aminohippuric acid before and 1 h after sham-PCNL or the PCNL surgical procedures. RESULTS: Control pigs that did not undergo surgery showed no significant change in renal plasma flow over the experimental observation period. In contrast, a single-needle stick to access the urinary collecting system resulted in renal vasoconstriction (25% reduction in renal plasma flow, P<0.05). Single-needle access plus creation of the nephrostomy tract did not lead to a further decline in renal plasma flow. CONCLUSIONS: The renal vasoconstriction observed after PCNL surgery is largely due to the act of inserting a needle into the kidney for percutaneous access to the urinary collecting system.

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