MP33-09 GLANSECTOMY AND NEOGLANS RECONSTRUCTION USING SPLIT-THICKNESS SKIN GRAFT / ACELLULAR DERMAL MATRIX FOR PENILE CANCER

Abstract

You have accessJournal of UrologyCME1 Apr 2023MP33-09 GLANSECTOMY AND NEOGLANS RECONSTRUCTION USING SPLIT-THICKNESS SKIN GRAFT / ACELLULAR DERMAL MATRIX FOR PENILE CANCER Haijun Yao, Dachao Zheng, Jianshu Ni, Xiang Wan, and Zhong Wang Haijun YaoHaijun Yao More articles by this author , Dachao ZhengDachao Zheng More articles by this author , Jianshu NiJianshu Ni More articles by this author , Xiang WanXiang Wan More articles by this author , and Zhong WangZhong Wang More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003266.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Penectomy as the traditional surgical treatment of penile cancer has substantial adverse functional and psychological impact. Organ-sparing surgery is recommended in selected penile cancer patients.Glansectomy and Neoglans reconstruction aims to provide curative resection while maximizing functional outcomes and minimizing psychological harm.To show the efficacy and safety of glansectomy and neoglans reconstruction using split-thickness skin graft (STSG) and Acellular Dermal Matrix (ADM). METHODS: Using our prospectively derived database, we identified 25 patients with penile squamous-cell carcinoma involving the glans, who were treated using glansectomy and neoglans reconstruction between March 2015 and December 2021. All the patients underwent total glansectomy and reconstruction of a new glans, of whom 18 (82%) with STSG and 7 with ADM. Deep spongiosal biopsies are taken to exclude invasion as a standard practice. The glans is excised and a neoglans is created using STSG/ADM. These 25 patients represent the subject of our study (mean age 57 years, range 45 to 71 years). RESULTS: 92% of patients (23/25) reported to be fully satisfied with the postoperative aesthetic appearance. The apex of corpora cavernosa was transected in 5 cases due to local invasion. Positive surgical margins were no detected in all the cases. 2 patients (8%) experienced local recurrence during the follow-up period. 4 patients had early partial loss of the graft (STSG 2 vs ADM 2). Two late complications occurred with urethral meatus stricture. CONCLUSIONS: Glansectomy and Neoglans reconstruction using STSG/ADM comprise a safe procedure in terms of oncologic control and complications for patients with penile cancer confined to the glans. Further studies are required to assess functional and sexual outcomes in these patients.The overall satisfaction rate and recovery of the sexual function are acceptable, and it can be considered an ideal procedure to treat superficial penile cancer. Source of Funding: The Project of Biobank (No. YBKB202119) from Shanghai 9th People's Hospital,Shanghai Jiao Tong University,School of Medicine © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e453 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Haijun Yao More articles by this author Dachao Zheng More articles by this author Jianshu Ni More articles by this author Xiang Wan More articles by this author Zhong Wang More articles by this author Expand All Advertisement PDF downloadLoading ...