MP32-17 THE IMPACT OF ETHNICITY ON PROSTATE CANCER-SPECIFIC MORTALITY IN CANADA

Abstract

You have accessJournal of UrologyProstate Cancer: Epidemiology & Natural History II (MP32)1 Sep 2021MP32-17 THE IMPACT OF ETHNICITY ON PROSTATE CANCER-SPECIFIC MORTALITY IN CANADA Noah Stern, Tina Luu Ly, Blayne Welk, Joseph Chin, Dale Ballucci, Michael Haan, and Nicholas Power Noah SternNoah Stern More articles by this author , Tina Luu LyTina Luu Ly More articles by this author , Blayne WelkBlayne Welk More articles by this author , Joseph ChinJoseph Chin More articles by this author , Dale BallucciDale Ballucci More articles by this author , Michael HaanMichael Haan More articles by this author , and Nicholas PowerNicholas Power More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002036.17AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The purported increased risk of early, aggressive disease has led to the classification of men of African descent as high risk with subsequent recommendations of more aggressive screening practices in these men. However, the underlying data for these recommendations lack high quality evidence, leaving the validity of these conclusions uncertain. Canadian healthcare data is uniquely suited to study the impact of ethnicity on prostate cancer mortality due to its diverse population and universal healthcare. METHODS: This retrospective cohort study uses Statistics Canada’s Canadian Census Health and Environment Cohort linking the mandatory 1991 long form census with healthcare, tax, and mortality databases to investigate the role of ethnicity on prostate cancer mortality. All men diagnosed with prostate cancer between 1992 and 2010 were included. Cox proportional-hazards models were used to predict the association between ethnicity and mortality accounting for immigrant status, age, and education. RESULTS: 51,530 cases of prostate cancer diagnosed between 1992 and 2010 (table 1). 29,705 of these men died with 7,925 of these deaths caused by prostate cancer. Non-minority men had higher or equivalent rates of prostate cancer-specific mortality compared to all visible minority groups (table 2). South Asian (HR 0.53 95% CI 0.36-0.76) and East Asian men (HR 0.62 95% CI 0.49-0.79) were seen to be at lower risk compared to non-visible minorities while Black men showed no increased risk (HR 0.83 95% CI 0.67-1.02). CONCLUSIONS: South and East Asian men were found to have lower risks of prostate cancer-specific mortality while there was no increased risk seen in black men. Black men have traditionally been classified as a high-risk prostate cancer population. However, it is unclear whether these risks are truly due to the cancer or whether there are social and societal barriers confounding the poor outcomes. Our study highlights the importance of addressing socioeconomic and cultural barriers to healthcare and the need for caution when drawing conclusions from observational studies. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e573-e573 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Noah Stern More articles by this author Tina Luu Ly More articles by this author Blayne Welk More articles by this author Joseph Chin More articles by this author Dale Ballucci More articles by this author Michael Haan More articles by this author Nicholas Power More articles by this author Expand All Advertisement Loading ...