MP3-14 GERMAN VALIDATION OF A PATIENT-REPORTED OUTCOME MEASURE (PROM) FOR URETHRAL STRICTURE SURGERY: A PROSPECTIVE STUDY AT A TERTIARY CARE CENTER

Abstract

You have accessJournal of UrologyTrauma/Reconstruction: Trauma & Reconstructive Surgery II1 Apr 2014MP3-14 GERMAN VALIDATION OF A PATIENT-REPORTED OUTCOME MEASURE (PROM) FOR URETHRAL STRICTURE SURGERY: A PROSPECTIVE STUDY AT A TERTIARY CARE CENTER Luis A. Kluth, Roland Dahlem, Philip Reiss, Tim Ludwig, Felix KH. Chun, Margit Fisch, and Sascha A. Ahyai Luis A. KluthLuis A. Kluth More articles by this author , Roland DahlemRoland Dahlem More articles by this author , Philip ReissPhilip Reiss More articles by this author , Tim LudwigTim Ludwig More articles by this author , Felix KH. ChunFelix KH. Chun More articles by this author , Margit FischMargit Fisch More articles by this author , and Sascha A. AhyaiSascha A. Ahyai More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.193AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Jackson and colleagues previously validated a PROM which is the only standardized questionnaire quantifying changes in voiding symptoms and health related quality of life (HRQoL) following urethral stricture surgery. We aimed to validate this instrument in a german single-center cohort in order to evaluate its psychometric properties and clinical utility. METHODS This was an institutional review board approved study. First, we translated the original questionnaire into German and retranslated it into English. We added the ICIQ UI short-form and the IIEF short-form to evaluate urinary incontinence and erectile function, respectively. Between 06/2012 and 05/2013, 62 patients were prospectively enrolled for anterior urethroplasty with buccal mucosa graft for urethral strictures. All patients completed the PROM preoperatively and at 3 months postoperatively. RESULTS Responsiveness: Total ICIQ-MLUTS scores decreased significantly from a median (mean) of 11 (11.2) preoperatively to 3 (4.9) postoperatively (p<0.001; 95% CI, 4.5-8.0). Qmax increased significantly from a median (mean) of 6.6 (7.8) preoperatively to 22.9 (26.1) postoperatively (p<0.001; 95% CI, 15.9-21.5). EQ-5D visual analogue scores improved significantly from a preoperative median (mean) of 80 (73) to 85 (78) postoperatively (p=0.016; 95% CI of the mean the difference 1-11). ICIQ-UI and IIEF scores did not change significantly (both p values ≥ 0.1). Internal consistency: Cronbach's alpha was 0.79 for the overall score and ranged between 0.71 and 0.81 with any one item deleted and demonstrated a high internal consistency. Item-total correlations were similarly high (0.32 to 0.72). Validity: There was a negative correlation between change in voiding symptom score (ICIQ MLUTS total score) and change in Qmax (p=0.001, -0.60) thus demonstrating high criterion validity. Fifty-five of 60 patients (92%) who completed the postoperative PROM reported being satisfied or very satisfied; 49 of whom (80%) felt their residual voiding symptoms interfered with their HRQoL a little or not at all. CONCLUSIONS In a prospective single-center study, we confirmed the PROM as a practical and robust instrument for assessing voiding symptoms and HRQoL following urethral stricture surgery. To our best knowledge, we validated the PROM into German for the first time; however, further validation studies are clearly needed. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e39 Advertisement Copyright & Permissions© 2014MetricsAuthor Information Luis A. Kluth More articles by this author Roland Dahlem More articles by this author Philip Reiss More articles by this author Tim Ludwig More articles by this author Felix KH. Chun More articles by this author Margit Fisch More articles by this author Sascha A. Ahyai More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...