MP31-20 URINARY INCONTINENCE AND QUALITY OF LIFE IN FEMALE-TO-MALE TRANSGENDER SUBJECTS ON HORMONE THERAPY

Abstract

You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Non-neurogenic Voiding Dysfunction II (MP31)1 Apr 2020MP31-20 URINARY INCONTINENCE AND QUALITY OF LIFE IN FEMALE-TO-MALE TRANSGENDER SUBJECTS ON HORMONE THERAPY Austin Fernstrum*, Al Ray, Britt Conroy, David Sheyn, and Juan Pablo del Rincon Austin Fernstrum*Austin Fernstrum* More articles by this author , Al RayAl Ray More articles by this author , Britt ConroyBritt Conroy More articles by this author , David SheynDavid Sheyn More articles by this author , and Juan Pablo del RinconJuan Pablo del Rincon More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000875.020AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To investigate whether lower urinary tract symptoms (LUTS) impact quality of life (QOL) in female-to-male transgender persons on chronic testosterone therapy. Secondarily, we aimed to identify patient-related physical and social factors that contribute to differences in QOL. METHODS: Transgender female-to-male subjects, 18 years or older, treated with testosterone for at least 12 months were recruited from a public health care system. Subjects were excluded if they had prior surgery for incontinence, pelvic organ prolapse, or gender affirmation or an active urinary tract infection. LUTS were assessed using the American Urologic Association Symptom Score (AUASS) and the International Consultation on Incontinence Questionnaire (ICIQ). The WHOQOL-BREF instrument was used to investigate QOL, and the CES-D 8 instrument was used to screen for depression. T-test and Chi-square were used to compare continuous and categorical variables, respectively. The relationship between patient factors and QOL was evaluated using multivariable logistic regression. RESULTS: Overall, 141 transmen were included in the study. Subjects were subdivided into two cohorts based on presence of urinary incontinence defined by the ICIQ score. In the incontinence group [n=49, (34.8%)], individuals were older [30.6 vs 26.2 years, p =0.01], had a higher body mass index (BMI) [p=0.015], and cigarette smoking history [p=0.01] compared to those without incontinence [n=92 (65.2%)]. The incontinence group had a higher prevalence of positive screening for depression [63.3 vs 39.1%, p=0.006] and were more frequently classified as having a poor QOL index [20.4 vs 3.3%, p=0.0008]. On multivariate analysis, limited medical transportation [aOR: 0.23, CI: 0.06-0.91], lack of money for food [aOR: 0.23, CI: 0.07-0.90], and increased BMI [aOR: 0.92, CI: 0.86-0.99] were factors influencing poor QOL. CONCLUSIONS: Presence of incontinence in female-to-male transgender persons is associated with increased age, higher BMI, and smoking history. Despite these findings, presence of LUTS was not found to be independently associated with QOL after adjusting for psychosocial factors. Source of Funding: National Institute of Diabetes and Digestive and Kidney Disease (NIDDK) grant, 5K12DK100014 © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e482-e483 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Austin Fernstrum* More articles by this author Al Ray More articles by this author Britt Conroy More articles by this author David Sheyn More articles by this author Juan Pablo del Rincon More articles by this author Expand All Advertisement PDF downloadLoading ...