MP30-14 SURVIVAL OUTCOMES FROM DCD RENAL TRANSPLANT ARE COMPARABLE TO DBD TRANSPLANTS FROM KIDNEYS PROCURED FROM DONORS OVER 50 YEARS OF AGE: UNOS/OPTN ANALYSIS

Abstract

You have accessJournal of UrologyTransplantation & Vascular Surgery: Renal Transplantation & Vascular Surgery II1 Apr 2017MP30-14 SURVIVAL OUTCOMES FROM DCD RENAL TRANSPLANT ARE COMPARABLE TO DBD TRANSPLANTS FROM KIDNEYS PROCURED FROM DONORS OVER 50 YEARS OF AGE: UNOS/OPTN ANALYSIS Patrick Luke, Hemant Sharma, Jingwen Chen, and Alp Sener Patrick LukePatrick Luke More articles by this author , Hemant SharmaHemant Sharma More articles by this author , Jingwen ChenJingwen Chen More articles by this author , and Alp SenerAlp Sener More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.947AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES There is hesitancy when utilizing DCD grafts of older age. We assess the long-term graft/ patient survival outcomes in donation after cardiac death ( DCD) and donation after brain death (DBD) transplants from kidneys procured from donors > 50 years of age. METHODS Utilizing the UNOS/OPTN database, we analyzed 14288 deceased donor kidney transplants (1833 DCD and 13533 DBD) from donors > 50 years between 2005-2013. Analysis of graft and patient survival was with multivariate regression analysis and Cox models with single imputation by dummy variable method to manage missing data. RESULTS Donor and recipient demographics between DCD and DBD recipients were similar including donor age, BMI, history of diabetes, and smoking. However, KDRI Rao was 1.5 (1.06-3.31) in DCD and 1.6 in DBD (1.6 (0.96-4.1), which was significant (p<0.001). Death censored graft survival in patients receiving grafts from donors >50 years at 1 and 5 years was 90 and 76% in DCD group vs 92% and 77% in DBD (p = NS). Furthermore, patient survival was 90 and 70% in DCD vs. 91 and 72% in DBD ( p = NS). When analyzing patients receiving grafts >60 years of age, graft survival was similar between DCD and DBD groups, but patient survival was inferior in the DCD group (p<0.05). CONCLUSIONS Results of renal transplantation with grafts >50 years are similar between DCD and DBD recipients, but caution should be taken when utilizing grafts >60 years. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e394-e395 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Patrick Luke More articles by this author Hemant Sharma More articles by this author Jingwen Chen More articles by this author Alp Sener More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...