MP3-10 REDUCTION OF ENLARGED PROSTATE DECREASES THE INCIDENCE OF INGUINAL HERNIA

Abstract

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology I1 Apr 2015MP3-10 REDUCTION OF ENLARGED PROSTATE DECREASES THE INCIDENCE OF INGUINAL HERNIA Yu-Hua Fan, Hsiao-Jen Chung, Eric Huang, Alex Lin, and Kuang-Kuo Chen Yu-Hua FanYu-Hua Fan More articles by this author , Hsiao-Jen ChungHsiao-Jen Chung More articles by this author , Eric HuangEric Huang More articles by this author , Alex LinAlex Lin More articles by this author , and Kuang-Kuo ChenKuang-Kuo Chen More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.113AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Patients with benign prostatic obstruction may need to strain to void and this effort over time may have a direct impact on the abdominal wall contributing to the development of inguinal hernia (IH). Furthermore, the published data showed that patients with IH present higher intensity of lower urinary tract symptoms. It is interesting to know whether transurethral prostatectomy for benign prostatic hyperplasia (BPH) could reduce the incidence of IH. METHODS We recruited male patients who were newly diagnosed with BPH and aged 50 years or older from a urology dataset including 3,431,366 individuals selected from the National Health Insurance Research Database for the year 2006 to 2010. According to treatment strategies, patients were assigned to one of the following categories: transurethral resection of prostate (TURP), alpha-1 blockers only, 5alpha-reductase inhibitors ± alpha-1 blockers. All subjects were followed up to the end of 2010 or the development of IH. Patients were excluded if they had prostatic cancer, constipation, chronic obstructive pulmonary disease, or IH developed within 6 months of diagnosis of BPH. The age-adjusted cox time-dependent model was used to calculate the risk of IH between different treatment groups. RESULTS We identified 171965 incident male patients with newly diagnosed BPH. Of the BPH patients, 8294 (4.82 %) underwent TURP (TURP group), 151753 (88.25%) received alpha-1 blockers only (AB group), 11918 (6.93%) received 5alpha-reductase inhibitors plus alpha-1 blockers or not (5ARI group). The incidences of IH in different treatment group were as follows: 93 (1.12%) in TURP group, 2334 (1.54%) in AB group, 147 (1.23%) in 5ARI group. Both the incidences of IH in TURP and 5ARI group were significantly lower than that in AB group (both P < 0.001). There was no difference in incidence rates of IH between TURP and 5ARI group. We further subdivided the TURP group into two subgroups according the weight of resected specimens and these were < 15 gm and >=15 gm. There was no difference in incidence rates of IH between the two subgroups of TURP. No matter what the weight of the resected specimens, no significant differences in incidence rates of IH were noted between TURP and 5ARI group. However, both subgroups of TURP group have significantly lower incidence rates of IH than AB group (both P < 0.001). CONCLUSIONS Prostate size-reducing treatments, including TURP and 5ARI, could significantly reduce the incidence of inguinal hernia in BPH patients compared with alpha-1 blockers. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e22 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Yu-Hua Fan More articles by this author Hsiao-Jen Chung More articles by this author Eric Huang More articles by this author Alex Lin More articles by this author Kuang-Kuo Chen More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...