MP29-13 CORPOROPLASTY WITH SMALL INTESTINE SUBMUCOSA IN PATIENTS WITH PEYRONIE'S DISEASE

Abstract

You have accessJournal of UrologyTrauma/Reconstruction: Ureter, Bladder, External Genitalia and Urotrauma II1 Apr 2015MP29-13 CORPOROPLASTY WITH SMALL INTESTINE SUBMUCOSA IN PATIENTS WITH PEYRONIE'S DISEASE Ramon Virasoro, Oscar A. Storme, Kenneth J. Delay, Jeremy B. Tonkin, Jack M. Zuckerman, Kurt A. Mccammon, and Gerald H. Jordan Ramon VirasoroRamon Virasoro More articles by this author , Oscar A. StormeOscar A. Storme More articles by this author , Kenneth J. DelayKenneth J. Delay More articles by this author , Jeremy B. TonkinJeremy B. Tonkin More articles by this author , Jack M. ZuckermanJack M. Zuckerman More articles by this author , Kurt A. MccammonKurt A. Mccammon More articles by this author , and Gerald H. JordanGerald H. Jordan More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.616AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Peyronie's disease (PD) is a disorganized collagen deposition of the tunica albuginea. Genetic predisposition, trauma and inflammation may play an important role. Prevalence ranges from 3% to 9%. PD has significant psychological burden and difficulty with intercourse. Surgical alternatives for PD include corporeal plication, plaque incision and grafting, and penile prosthesis implantation. No single surgical method has emerged as the most favorable for every patient. The use of Autograft and Xenografts, such as dermis or small intestine submucosa (SIS) has shown benefits. The objective of this study is to report our experience with SIS. METHODS Retrospective chart review of all adult men with PD that underwent corporoplasty with SIS between January 1, 1999 and August 1, 2014. Photographs of the penis in erection were used to measure curvature; all patients with Erectile Dysfunction (ED) had preoperative penile duplex ultrasound. Penile X-ray was obtained if calcified plaque was suspected. Data collection included: demographics, preoperative evaluation, outcomes, and intra- and post-operative complications. Success was considered curvature correction with residual curvature ≤15 degrees. Secondary outcome was postoperative ED. We analyzed categorical data with chi2, and continuous data with t-test; statistical analysis was carried out using Graph Pad software. RESULTS Fifty-two patients, mean age 54.99 years (SD: +/-8.35), were included. Diabetes mellitus (23.1%), dyslipidemia (51.9%), hypertension (27.9%), and penile trauma (30.76%) were observed. Time from onset to surgery was 10 to 240 months; mean 35.02 months (SD: +/- 37.96). Curvature was dorsal in all. Mean preoperative curvature degree was 68.7 (SD+/-: 20.97). After a mean follow up of 5.71 month (SD: +/- 4.89 month), curvature correction was achieved in 82.7% patients. Postoperative ED was registered in 16.6%. Complications were observed in 4 patients. There was no statistically significant difference between postoperative ED and Diabetes mellitus (p=0.53) or with ≥90 degrees of preoperative curvature (p=0.59) CONCLUSIONS Penile curvature correction with SIS is safe and efficacious for patients with PD. We found no association of postop ED with co-morbid diseases, or preop curvature degree. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e344 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Ramon Virasoro More articles by this author Oscar A. Storme More articles by this author Kenneth J. Delay More articles by this author Jeremy B. Tonkin More articles by this author Jack M. Zuckerman More articles by this author Kurt A. Mccammon More articles by this author Gerald H. Jordan More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...