MP27-13 PREVALENCE AND PREDICTORS OF UNRECOGNIZED LOW SEXUAL DESIRE IN MEN WITH NEW ONSET ERECTILE DYSFUNCTION—FINDINGS FROM A CROSS-SECTIONAL, REAL-LIFE STUDY

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Evaluation I (MP27)1 Sep 2021MP27-13 PREVALENCE AND PREDICTORS OF UNRECOGNIZED LOW SEXUAL DESIRE IN MEN WITH NEW ONSET ERECTILE DYSFUNCTION—FINDINGS FROM A CROSS-SECTIONAL, REAL-LIFE STUDY Luca Boeri, Paolo Capogrosso, Walter Cazzaniga, Luigi Candela, Giuseppe Fallara, Edoardo Pozzi, Federico Belladelli, Nicolò Schifano, Daniele Cignoli, Gianmarco Colandrea, Massimiliano Raffo, Costantino Abbate, Francesco Montorsi, and Andrea Salonia Luca BoeriLuca Boeri More articles by this author , Paolo CapogrossoPaolo Capogrosso More articles by this author , Walter CazzanigaWalter Cazzaniga More articles by this author , Luigi CandelaLuigi Candela More articles by this author , Giuseppe FallaraGiuseppe Fallara More articles by this author , Edoardo PozziEdoardo Pozzi More articles by this author , Federico BelladelliFederico Belladelli More articles by this author , Nicolò SchifanoNicolò Schifano More articles by this author , Daniele CignoliDaniele Cignoli More articles by this author , Gianmarco ColandreaGianmarco Colandrea More articles by this author , Massimiliano RaffoMassimiliano Raffo More articles by this author , Costantino AbbateCostantino Abbate More articles by this author , Francesco MontorsiFrancesco Montorsi More articles by this author , and Andrea SaloniaAndrea Salonia More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002024.13AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The interrelationship between male sexual desire and erectile dysfunction (ED) has been variously investigated. We aimed to investigate the prevalence and the predictors of unrecognized low sexual desire (LSD) in a cohort of men seeking medical help for new onset ED in the real-life setting. METHODS: Data from 1509 men seeking first medical help for new-onset ED at a single andrology centre in 2010-2020 were analyzed. Patients were assessed with a thorough medical and sexual history. Comorbidities were scored with the Charlson Comorbidity Index (CCI). All participants were asked to self-report the presence of LSD and to complete the International Index of Erectile Function (IIEF) and the Beck Depression Inventory (BDI). Depressive symptoms were defined as BDI≥11. The median value of the IIEF-Sexual desire domain (IIEF-SD) was used to categorize the cohort in low SD (IIEF-SD<7, defined as unrecognized LSD) vs. normal SD (IIEF-SD≥7). The IIEF-Erectile function (IIEF-EF) domain was categorized according to Cappelleri’s criteria. Serum hormones were measured in every patient. Hypogonadism was defined as total testosterone (tT)<3.0 ng/mL. Descriptive statistics and logistic regression models tested the association between clinical variables and unrecognized LSD. RESULTS: Overall, 312 (20.7%) patients self-reported LSD and were excluded from further analyses. Of 1197 patients not self-reporting LSD, 369 (30.8%) had IIEF-SD<7. Patients with unrecognized LSD were older [median (IQR) 54 yrs (41-63) vs. 49 (36-59)], had lower IIEF-EF [10 (5-20) vs. 22 (11-28)], higher BDI [6 (3-12) vs. 4 (1-8)] and lower tT [4.3 (3.2-5.7) vs. 4.7 (3.2-7.3) ng/ml] (all p<0.001) than men without LSD. Men with unrecognized LSD presented a higher rate of severe ED (50% vs. 24%, p<0.001), of BDI≥11 (30.6% vs. 18.3%) and tT<3.0ng/mL (19.9% vs. 10%) (all p<0.001). At multivariable logistic regression analysis, lower tT (OR 0.91, p=0.03), lower IIEF-EF (OR 0.94, p<0.001) and BDI≥11 (OR 1.83, p<0.001) were found to be independent predictors of unrecognized LSD, after accounting for age. CONCLUSIONS: One out of three men seeking first medical help for ED showed unrecognized LSD. Men with unrecognized LSD were older, had more severe ED and depressive symptoms and lower tT values despite not suggestive for hypogonadism than men with normal SD. Thus, a detailed investigation of sexual desire should be always included in the diagnostic work-up of men with ED. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e476-e476 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Luca Boeri More articles by this author Paolo Capogrosso More articles by this author Walter Cazzaniga More articles by this author Luigi Candela More articles by this author Giuseppe Fallara More articles by this author Edoardo Pozzi More articles by this author Federico Belladelli More articles by this author Nicolò Schifano More articles by this author Daniele Cignoli More articles by this author Gianmarco Colandrea More articles by this author Massimiliano Raffo More articles by this author Costantino Abbate More articles by this author Francesco Montorsi More articles by this author Andrea Salonia More articles by this author Expand All Advertisement Loading ...