MP27-06 RISK FACTORS ASSOCIATED WITH FECAL INCONTINENCE IN PATIENTS WITH OVERACTIVE BLADDER

Abstract

You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Incontinence: Evaluation (Urodynamic Testing)1 Apr 2018MP27-06 RISK FACTORS ASSOCIATED WITH FECAL INCONTINENCE IN PATIENTS WITH OVERACTIVE BLADDER Caitlin Lim, Joshua Cohn, Casey Kowalik, Melissa Kaufman, Roger Dmochowski, and W. Stuart Reynolds Caitlin LimCaitlin Lim More articles by this author , Joshua CohnJoshua Cohn More articles by this author , Casey KowalikCasey Kowalik More articles by this author , Melissa KaufmanMelissa Kaufman More articles by this author , Roger DmochowskiRoger Dmochowski More articles by this author , and W. Stuart ReynoldsW. Stuart Reynolds More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.885AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Overactive bladder (OAB) and bowel conditions often occur together, and both can have profound effects on a woman′s quality of life. Treatment of OAB can impact bowel function as well, either negatively (e.g. constipation and antimuscarinics), or positively (e.g. reduced fecal incontinence, FI, with sacral neuromodulation). We sought to identify factors associated with FI in a community-based sample of women with OAB. METHODS Adult women with symptoms of OAB were identified via clinical practice and email-based advertisements. In all subjects, OAB was confirmed by a score of 4 on the OABv3 screening questionnaire. Standardized questionnaires assessed clinical characteristics, OAB severity (OAB-q8), quality of life (OAB-q SF HRQoL), and FI (Fecal Incontinence Severity Index, FISI). These data were compared between subjects with and without FI, defined as any leakage of mucus, liquid or solid stool at least monthly, and the association between OAB and FI severity assessed. RESULTS 101 (53%) participants reported having FI and 91 (47%) did not. Mean FISI scores were 27.9 ± 8.6 in those reporting FI and 5.5 ± 5.2 in those reporting no FI (p<0.001). Women reporting FI had more severe OAB (mean OABq8 SS: 47.5 ± 25.6 vs. 39.3 ± 21.2, p=0.017) and worse OAB-HRQL (59.6 ± 29.5 vs 69.3 ± 23.0, p=0.012). OAB severity (OABq8) (β 0.29, 95% 0.04-0.55) and OAB-related quality of life (OABq-SF HRQL) (β -0.33, 95% CI -0.61, -0.05) were significantly correlated with FISI scores. In addition to suffering from more severe OAB, women reporting any FI were older (mean age 46.8 ± 15.2 vs. 41.6 ± 14.0 years, p=0.015) and more likely to report suffering from neuropathy (p=0.013), spine or degenerative disc disease (p=0.003), irritable bowel syndrome (p=0.013), fibromyalgia (p=0.035), and chronic fatigue syndrome (p=0.044). CONCLUSIONS Over half of women with OAB reported at least monthly FI, which was associated with increased age and the presence of neuropathy, degenerative spinal disease, irritable bowel syndrome, and chronic pain syndromes. Furthermore, FI was associated with increased OAB symptom severity and decreased OAB condition-specific quality of life. In many patients, FI and OAB may be unique symptoms resulting from common pathophysiology, either due to pelvic organ or more global dysfunction. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e348 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Caitlin Lim More articles by this author Joshua Cohn More articles by this author Casey Kowalik More articles by this author Melissa Kaufman More articles by this author Roger Dmochowski More articles by this author W. Stuart Reynolds More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...