MP25-19 EFFICACY OF RECTAL POVIDONE-IODINE SWABS IN DECREASING INFECTIOUS COMPLICATIONS AFTER TRANSRECTAL PROSTATE BIOPSY

Abstract

biopsies (USTRPB) is a long-standing and current practice in many centers around the globe. Strong evidence supporting such recommendation is lacking. The objective of the present trial is to analyze the difference in complications among patients with and without pre-biopsy enemas. METHODS: Single center, randomized prospective study. We included patients scheduled for USTRPB in our Institution (march 2013-ongoing). One group (A) applied two glycine enemas and the other (B) did not apply any enemas. Urinalysis and urine culture were performed prior and 5 days post-biopsy. A clinical evaluation was performed 10 days after the biopsy. Clinical complications were defined as need for hospitalization, sepsis or urinary retention. A “visualization score” was done by the urologist performing the biopsy (blinded to the study). IBM SPSS Statistics Version 22 was used for data analysis. Chi square analysis was used for categorical variables and Student-T for comparing means with normal distributions. RESULTS: 139 patients were included. Mean age was 64.79 (48-93) years old. 33.9% were hypertensive and 21.4% diabetic. All patients had a pre-biopsy urine culture (96% were negative and 4% received culture guided treatment). 56.5% used enemas. PostUSTRPB complications and visualization scores are shown in table. Other complains after biopsy were hematuria (74.1%), hematospermia (29.5%), rectal bleeding (40.2%) and fever (12.5%), without group differences. 31.8% of patients had prostate cancer, without any group differences. CONCLUSIONS: Our preliminary data shows that the routine use of pre-biopsy rectal enema did not lead to a significant decrease in terms of complications, visualization or diagnostic accuracy when compared to the absence of pre-biopsy enemas. Further more, the omission of pre-biopsy enemas could result in a cost and discomfort reduction to the patient.