MP23-13 TRANSFUSION-DEPENDENT GROSS HEMATURIA REQUIRING SURGICAL MANAGEMENT: ARE OUTCOMES WORSE AMONG PATIENTS WITH PREVIOUS PELVIC RADIATION?

Abstract

You have accessJournal of UrologyInfections/Inflammation/Cystic Disease of the Genitourinary Tract: Kidney & Bladder II1 Apr 2017MP23-13 TRANSFUSION-DEPENDENT GROSS HEMATURIA REQUIRING SURGICAL MANAGEMENT: ARE OUTCOMES WORSE AMONG PATIENTS WITH PREVIOUS PELVIC RADIATION? Matthew D Grimes, Brady L Miller, Tyler Wittmann, Sarah E McAchran, David F Jarrard, Wade A Bushman, Daniel H Williams, Tracy M Downs, Kyle A Richards, Sara L Best, and E. Jason Abel Matthew D GrimesMatthew D Grimes More articles by this author , Brady L MillerBrady L Miller More articles by this author , Tyler WittmannTyler Wittmann More articles by this author , Sarah E McAchranSarah E McAchran More articles by this author , David F JarrardDavid F Jarrard More articles by this author , Wade A BushmanWade A Bushman More articles by this author , Daniel H WilliamsDaniel H Williams More articles by this author , Tracy M DownsTracy M Downs More articles by this author , Kyle A RichardsKyle A Richards More articles by this author , Sara L BestSara L Best More articles by this author , and E. Jason AbelE. Jason Abel More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.741AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Gross hematuria requiring blood transfusion is uncommon, and few studies have evaluated management or long term outcomes after initial surgical treatment. Here, we characterize patients undergoing surgical management of transfusion dependent hematuria and evaluate post-surgical outcomes. We hypothesized that patients who had received prior pelvic radiation would have worse postoperative outcomes. METHODS Following IRB approval, comprehensive clinical information was collected and analyzed for patients with hematuria requiring blood transfusion and inpatient surgical management from 2000-2015. RESULTS Seventy patients requiring surgery for transfusion dependent hematuria were identified, including 30 (42.9%) who had received prior pelvic radiation. Hematuria was due to radiation cystitis in 20 (28.6%), post operative bleeding in 12 (17.1%), traumatic catheterization in 10 (14.3%), benign prostatic bleeding in 6 (8.57%), bladder cancer in 5 (7.14%), prostate cancer in 5 (7.14%), hemorrhagic cystitis in 4 (5.71%), and other causes in 8 (11.4%) patients. All 70 patients underwent cystoscopy with clot evacuation and fulguration. Concomitant operations performed included formalin instillation in 7, TURBT in 8, suprapubic tube placement in 4, and ligation of the bulbar arteries in 1 patient(s). Radiated patients were on average 9.3 years older than their non-radiated counterparts (p=0.01). Otherwise no significant differences were identified in baseline characteristics or with regards to LOS, 90 day readmission rate, or likelihood of indwelling catheterization at discharge (Table). At median follow up of 10.9 (IQR 3.7-26.5) months, radiated patients required on average 1.9 additional surgical procedures compared to 1.4 without prior radiation (p=0.21). Previously radiated patients were more likely to require long term urinary diversion compared to non-radiated patients, 9 (31.0%) versus 3 (8.3%) patients (p=0.02). CONCLUSIONS Pelvic radiation is a common etiology for transfusion dependent hematuria. While initial post-operative outcomes were similar, one third of patients with transfusion dependent hematuria and prior radiation required urinary diversion for long term management. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e298 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Matthew D Grimes More articles by this author Brady L Miller More articles by this author Tyler Wittmann More articles by this author Sarah E McAchran More articles by this author David F Jarrard More articles by this author Wade A Bushman More articles by this author Daniel H Williams More articles by this author Tracy M Downs More articles by this author Kyle A Richards More articles by this author Sara L Best More articles by this author E. Jason Abel More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...