MP22-12 POSTOPERATIVE OUTCOME OF CYSTIC RENAL CELL CARCINOMA DEFINED ON PREOPERATIVE IMAGING: A RETROSPECTIVE STUDY

Abstract

You have accessJournal of UrologyKidney Cancer: Epidemiology & Evaluation/Staging I1 Apr 2017MP22-12 POSTOPERATIVE OUTCOME OF CYSTIC RENAL CELL CARCINOMA DEFINED ON PREOPERATIVE IMAGING: A RETROSPECTIVE STUDY Taesoo Choi, Jun Phil Na, CHUNG UN LEE, Hyunwoo Chung, SEUNGHEE YUM, Hyun Hwan Sung, Hwang Gyun Jeon, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee, Han Yong Choi, Chan Kyo Kim, and Byong Chang Jeong Taesoo ChoiTaesoo Choi More articles by this author , Jun Phil NaJun Phil Na More articles by this author , CHUNG UN LEECHUNG UN LEE More articles by this author , Hyunwoo ChungHyunwoo Chung More articles by this author , SEUNGHEE YUMSEUNGHEE YUM More articles by this author , Hyun Hwan SungHyun Hwan Sung More articles by this author , Hwang Gyun JeonHwang Gyun Jeon More articles by this author , Seong Il SeoSeong Il Seo More articles by this author , Seong Soo JeonSeong Soo Jeon More articles by this author , Hyun Moo LeeHyun Moo Lee More articles by this author , Han Yong ChoiHan Yong Choi More articles by this author , Chan Kyo KimChan Kyo Kim More articles by this author , and Byong Chang JeongByong Chang Jeong More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.666AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To evaluate postoperative outcome of cystic renal cell carcinoma (RCC) defined on preoperative computed tomography (CT), and to find the optimal cut-off of cystic cystic proportion in association with patients’ prognosis. METHODS In this institutional review board-approved study with waiver of informed consent, a total of 1315 patients who received surgery for single RCC with pre-operative CT were enrolled. The cystic proportion of RCC was determined on CT. The optimal cut-off of cystic proportion was explored regarding cancer-specific survival. The RCCs were categorized as cystic or non-cystic RCCs according to conventional (i.e. cystic proportion = 75%) and the optimal cut-off, and then post-operative outcomes were compared between the two groups. Multivariate Cox regression analysis was performed to determine the independent predictor for cancer-specific survival. RESULTS Of the 1315 lesions, 107 (8.1%) were identified as cystic RCCs according to a conventional cut-off. Postoperative outcome of cystic RCC was significantly better than that of non-cystic RCC (P<0.001). Neither metastasis nor recurrence in patients with cystic RCC was developed after surgery. In association with cancer-specific survival rate, the optimal cut-off of cystic proportion was 45%, and 197 (15.0%) were defined as cystic RCCs accordingly. On Cox regression analysis, cystic proportion = 45% in RCC was an independent predictor of favorable outcome regarding cancer-specific survival (hazard ratio 0.34, P = 0.03). CONCLUSIONS Cystic RCC defined on preoperative CT is associated with low metastatic potential and favorable outcomes after surgery. Particularly, cystic proportion = 45% is an independent prognostic factor for favorable survival. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e261 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Taesoo Choi More articles by this author Jun Phil Na More articles by this author CHUNG UN LEE More articles by this author Hyunwoo Chung More articles by this author SEUNGHEE YUM More articles by this author Hyun Hwan Sung More articles by this author Hwang Gyun Jeon More articles by this author Seong Il Seo More articles by this author Seong Soo Jeon More articles by this author Hyun Moo Lee More articles by this author Han Yong Choi More articles by this author Chan Kyo Kim More articles by this author Byong Chang Jeong More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...