MP20-02 QUANTITATIVE TRANSRECTAL SHEAR WAVE ELASTOSONOGRAPHY UNDERGOING SALVAGE EXTRAPERITONEAL LAPAROSCOPIC RADICAL PROSTATECTOMY FOLLOWING FAILED RADIOTHERAPY

Abstract

You have accessJournal of UrologyImaging/Radiology: Uroradiology II1 Apr 2018MP20-02 QUANTITATIVE TRANSRECTAL SHEAR WAVE ELASTOSONOGRAPHY UNDERGOING SALVAGE EXTRAPERITONEAL LAPAROSCOPIC RADICAL PROSTATECTOMY FOLLOWING FAILED RADIOTHERAPY Cheng Wei, Stephen Lang, Magdelena Szewczyk-Bieda, and Ghulam Nabi Cheng WeiCheng Wei More articles by this author , Stephen LangStephen Lang More articles by this author , Magdelena Szewczyk-BiedaMagdelena Szewczyk-Bieda More articles by this author , and Ghulam NabiGhulam Nabi More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.672AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To evaluate pre- surgical quantitative transrectal shear wave elastosonongraphy (SWE) in the detection and characterisation of radioresistant prostate cancer METHODS 12 men with recurrent prostate cancer following external beam radiotherapy were included in a prospective protocol driven study. All underwent MRI imaging and quantitative shear wave elastosonographic assessment of recurrent disease prior to salvage laparoscopic radical prostatectomy procedures. Images were used to construct 3-D mold printing and histopathological processing of surgical specimen. Statistical analysis including ROC were generated using software programmes. RESULTS There were 48 cancer foci identified on final histopathology using patient specific mold based approach in 12 patients. Mean number of lesion was 3.4 (range 2 to 4). Quantitative transrectal SWE showed a sensitivity and specificity 0.77 (95% CI 0.627 - 0.880) and 0.82 (95% CI 0.642 - 0.942) respectively. The diagnostic accuracy increased with increasing size of the lesions with overall AUC of 0.89. CONCLUSIONS In our series quantitative transrectal SWE showed a good diagnosed accuracy in the detection and characterisation of recurrent prostate cancer following failed radiotherapy treatment. These findings may help in targeting biopsies or future focal treatment options. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e252 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Cheng Wei More articles by this author Stephen Lang More articles by this author Magdelena Szewczyk-Bieda More articles by this author Ghulam Nabi More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...