MP19-17 TUMOR ZONALITY ON PREOPERATIVE MRI IS AN INDEPENDENT PREDICTOR FOR POSITIVE SURGICAL MARGIN AFTER RETZIUS-SPARING ROBOT-ASSISTED RADICAL PROSTATECTOMY

Abstract

You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy I (MP19)1 Apr 2020MP19-17 TUMOR ZONALITY ON PREOPERATIVE MRI IS AN INDEPENDENT PREDICTOR FOR POSITIVE SURGICAL MARGIN AFTER RETZIUS-SPARING ROBOT-ASSISTED RADICAL PROSTATECTOMY Youjian Li*, Xuefeng Qiu, and Hongqian Guo Youjian Li*Youjian Li* More articles by this author , Xuefeng QiuXuefeng Qiu More articles by this author , and Hongqian GuoHongqian Guo More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000852.017AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To investigate the influence of tumor zonality on positive surgical margin (PSM) after Retzius-sparing robot-assisted radical prostatectomy (RS-RARP). METHODS: Consecutive 203 patients with prostate cancer (PCa) who underwent RS-RARP in our center were divided into three cohorts according to the tumor zonal origin described on preoperative magnetic resonance imaging (MRI). Clinical and pathological characteristics outcomes were compared between the groups. Relationship of various tumor clinicopathological parameters to PSM after RS-RARP were evaluated. RESULTS: The rates of PSM in men with transition zone and mixed tumors were significantly higher than those with peripheral zone tumors (p = 0.001). 42.0% and 40.9% of the positive margins in patients with transition zone and mixed cancers were located at the anterior part of the gland, respectively. On multivariate analysis, transition zone tumor was significantly associated with higher PSM rates after RS-RARP (p = 0.007). Sub-analysis revealed that transition tumor in patients with high-risk cases had a higher risk of PSM after RS-RARP (p= 0.003). CONCLUSIONS: Transition zone tumor is an independent risk factor for PSM after RS-RARP. Preoperative identification of transition zone tumor might aid surgical planning with Retzius-sparing technique, especially for patients with high-risk PCa. Source of Funding: None © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e304-e304 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Youjian Li* More articles by this author Xuefeng Qiu More articles by this author Hongqian Guo More articles by this author Expand All Advertisement PDF downloadLoading ...