MP15-05 THE PREVALENCE AND GENOTYPE DISTRIBUTION OF HUMAN PAPILLOMAVIRUSES AMONG MEN IN KOREA

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You have accessJournal of UrologyCME1 Apr 2023MP15-05 THE PREVALENCE AND GENOTYPE DISTRIBUTION OF HUMAN PAPILLOMAVIRUSES AMONG MEN IN KOREA Hyun Soo Lee, Sun Tae Ahn, Wonku Hwang, Seon Beom Jo, Jong Wook Kim, Mi Mi Oh, Hong Seok Park, and Du Geon Moon Hyun Soo LeeHyun Soo Lee More articles by this author , Sun Tae AhnSun Tae Ahn More articles by this author , Wonku HwangWonku Hwang More articles by this author , Seon Beom JoSeon Beom Jo More articles by this author , Jong Wook KimJong Wook Kim More articles by this author , Mi Mi OhMi Mi Oh More articles by this author , Hong Seok ParkHong Seok Park More articles by this author , and Du Geon MoonDu Geon Moon More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003235.05AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Human papillomavirus (HPV) prevalence and genotype distribution are different between various nations and regions. Additionally, previous studies have mainly focused on HPV infection in women and epidemiological studies of HPV infection in men have been rarely reported. Therefore, we aimed to investigate the HPV infection status in men in Korea to establish vaccine-based HPV prevention strategies. METHODS: Between January 2014 to June 2022, samples of 44,065 men, who were volunteered for testing or recommended to be tested by a clinician, were tested for the HPV detection and genotyping. Samples were collected from the coronal sulcus, glans penis, shaft, and scrotum. HPV detection and typing was conducted using the Anyplex™ II HPV 28 Detection system, which detects 19 high-risk (HR) HPVs and 9 low-risk (LR) HPVs. This study was approved by Ethical Committee of the Korea University Hospital. RESULTS: Overall prevalence was 59.7%, and overall prevalence of HR and LR HPVs were 30.6% and 50.1%, respectively. The most prevalent genotypes of HR were 16 (5.2%), 53 (4.6%), 51 (4.2%), 52 (3.8%), 58 (3.7%), 39(3.6%) and 66(3.4%). Overall HPV prevalence was not associated with age. However, the prevalence of HR HPVs in teens (34.1%) and 20 s (33.8%) were significantly higher than in other age groups. Of the 26,299 men with HPV infection, 9259 (35.2%) had a genotype that could not prevented by the 9-valent vaccine. CONCLUSIONS: A significant number of infections of genotypes that were not prevented by 9-valent vaccine were observed. Based on this, it is considered necessary to evaluate the usefulness of developing HPV vaccination for men. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e193 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Hyun Soo Lee More articles by this author Sun Tae Ahn More articles by this author Wonku Hwang More articles by this author Seon Beom Jo More articles by this author Jong Wook Kim More articles by this author Mi Mi Oh More articles by this author Hong Seok Park More articles by this author Du Geon Moon More articles by this author Expand All Advertisement PDF downloadLoading ...