MP14-03 ROBOT-ASSISTED RADICAL NEPHRECTOMY AND INFERIOR VENA CAVA LEVEL I-III THROMBECTOMY: PERIOPERATIVE AND LONG-TERM ONCOLOGIC OUTCOMES

Abstract

You have accessJournal of UrologyKidney Cancer: Advanced (including Drug Therapy) I (MP14)1 Sep 2021MP14-03 ROBOT-ASSISTED RADICAL NEPHRECTOMY AND INFERIOR VENA CAVA LEVEL I-III THROMBECTOMY: PERIOPERATIVE AND LONG-TERM ONCOLOGIC OUTCOMES Umberto Anceschi, Aldo Brassetti, Maria Consiglia Ferriero, Gabriele Tuderti, Leonardo Misuraca, Alfredo Maria Bove, Riccardo Mastroianni, Alfredo Maria Bove, Salvatore Guaglianone, Monish Aron, Mihir Desai, Inderbir Gill, Michele Gallucci, and Giuseppe Simone Umberto AnceschiUmberto Anceschi More articles by this author , Aldo BrassettiAldo Brassetti More articles by this author , Maria Consiglia FerrieroMaria Consiglia Ferriero More articles by this author , Gabriele TudertiGabriele Tuderti More articles by this author , Leonardo MisuracaLeonardo Misuraca More articles by this author , Alfredo Maria BoveAlfredo Maria Bove More articles by this author , Riccardo MastroianniRiccardo Mastroianni More articles by this author , Alfredo Maria BoveAlfredo Maria Bove More articles by this author , Salvatore GuaglianoneSalvatore Guaglianone More articles by this author , Monish AronMonish Aron More articles by this author , Mihir DesaiMihir Desai More articles by this author , Inderbir GillInderbir Gill More articles by this author , Michele GallucciMichele Gallucci More articles by this author , and Giuseppe SimoneGiuseppe Simone More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000001995.03AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The aim of this study is to describe long-term oncologic outcomes of robot-assisted radical nephrectomy (RARN) with inferior vena cava tumor thrombectomy (IVCT) performed at a single-institution. METHODS: Between January 2014 and October 2018, 30 consecutive patients underwent RARN-IVCT for RCC and VTT for either curative (n=19) or cytoreductive intent (n=11) at a single tertiary-care center. Baseline, demographic and perioperative data were collected. A descriptive statistical analysis was performed. Frequencies and proportions were reported for categorical variables while medians and interquartile ranges (IQRs) were reported for continuously coded variables. Overall survival (OS), cancer-specific survival (CSS), local recurrence-free survival (LRFS) and metastasis-free (MFS) were computed by Kaplan-Meier curves for the entire cohort and compared by surgical indication with the log-rank test. RESULTS: All cases were succesfully completed without any conversion to open surgery. Median operative time was 360 minutes (IQR 240-390). Median estimated blood loss was 550 ml (IQR 225-1500). Fifteen patients (50%) required blood transfusions. Median hospital stay was 7 days (IQR 4-12.2). Overall, nineteen patients (63.3%) had perioperative complications, 15 Clavien grade 1-2 (50%) and 4 grade 3-5 (13.3%) complications, respectively. At a median follow-up of 31.1 months (IQR 18-52.9), LRFS, MFS, CSS and OS were 93.3%, 40%, 46.7% and 40%, respectively. No significant survival differences were noted according to surgical indication (each p>0.1). The small cohort, high rate of adjuvant targeted-therapies (46.7%) and extreme surgical complexity may affect reproducibility of outcomes. CONCLUSIONS: RARN-IVCT represents a feasible and safe surgical option in tertiary referral centers; long-term oncologic results seem to be comparable to those reported in open surgery literature. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e252-e253 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Umberto Anceschi More articles by this author Aldo Brassetti More articles by this author Maria Consiglia Ferriero More articles by this author Gabriele Tuderti More articles by this author Leonardo Misuraca More articles by this author Alfredo Maria Bove More articles by this author Riccardo Mastroianni More articles by this author Alfredo Maria Bove More articles by this author Salvatore Guaglianone More articles by this author Monish Aron More articles by this author Mihir Desai More articles by this author Inderbir Gill More articles by this author Michele Gallucci More articles by this author Giuseppe Simone More articles by this author Expand All Advertisement Loading ...