MP13-13 ASSOCIATION BETWEEN COMPLEXITY OF PELVIC SURGICAL FIELD AND OUTCOMES OF RADICAL CYSTECTOMY WITH URINARY DIVERSION

Abstract

You have accessJournal of UrologyCME1 May 2022MP13-13 ASSOCIATION BETWEEN COMPLEXITY OF PELVIC SURGICAL FIELD AND OUTCOMES OF RADICAL CYSTECTOMY WITH URINARY DIVERSION Leilei Xia, Raju Chelluri, Ruchika Talwar, Daniel Lee, and Thomas Guzzo Leilei XiaLeilei Xia More articles by this author , Raju ChelluriRaju Chelluri More articles by this author , Ruchika TalwarRuchika Talwar More articles by this author , Daniel LeeDaniel Lee More articles by this author , and Thomas GuzzoThomas Guzzo More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002542.13AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Surgical field can be complicated by prior pelvic surgery or radiation for patients undergoing radical cystectomy (RC) with urinary diversion (UD). However, whether the complexity of pelvic surgical field leads to worse perioperative outcomes is not well reported in the literature. METHODS: Patients who underwent RC and UD were identified from the 2019 National Surgical Quality Improvement Program (NSQIP) database. Pelvic surgical field complexity was categorized into 4 groups based on prior history of pelvic surgery and/or radiation: no pelvic surgery or radiation (n=893), pelvic surgery only (n=807), pelvic radiation only (n=73), pelvic surgery and radiation (n=147). Outcomes of interest were derived from NSQIP outcomes within 30 days from surgery and included: any complications, major complications, prolonged operative time (pOT, ≥400 min), prolonged length of stay (pLOS, ≥9 d), discharged to continued care, and unplanned readmission. RESULTS: A total of 1,920 patients (ileal conduit=1,628, neobladder=292) were included; 22.9% had robotic approach and 36.4% had preoperative chemotherapy. Overall complication rate in the cohort was 59% and major complication rate was 25.8 %. The outcomes stratified by the complexity of pelvic surgical field are shown in the Figure. Multivariable logistic regression showed that compared with no pelvic surgery or radiation, pelvic surgery only (odds ratio [OR]=1.43, 95% confidence interval [CI]=1.13-1.81, P=0.003) and pelvic radiation only (OR=1.98, 95%CI=1.13-3.46, P=0.016) were associated with higher odds of pOT but not other outcomes. Pelvic surgery and radiation group was associated with higher odds of major complications (OR=1.47, 95%CI=1.00-2.16, P=0.052), pOT (OR=1.84, 95%CI=1.22-2.77, P=0.004), and pLOS (OR=1.49, 95%CI=1.00-2.24, P=0.049). CONCLUSIONS: This is the first national study focusing on the complexity of pelvic surgical field and outcomes of RC. This NSQIP study, although limited by sample size, showed increased complexity of pelvic surgical field was associated with longer OT, longer hospital stays, and likely higher complication rates. Our study will add to literature improving patient counseling for a group of challenging bladder cancer patients who had prior history of pelvic surgery and pelvic radiation, especially those who had both. Source of Funding: None © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e226 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Leilei Xia More articles by this author Raju Chelluri More articles by this author Ruchika Talwar More articles by this author Daniel Lee More articles by this author Thomas Guzzo More articles by this author Expand All Advertisement PDF DownloadLoading ...