MP12-07 THE IMPLICATION OF AORTIC CALCIFICATION ON PERSISTENT HYPERTENSION AFTER LAPAROSCOPIC ADRENALECTOMY IN PATIENTS WITH PRIMARY ALDOSTERONISM

Abstract

You have accessJournal of UrologyAdrenal1 Apr 2016MP12-07 THE IMPLICATION OF AORTIC CALCIFICATION ON PERSISTENT HYPERTENSION AFTER LAPAROSCOPIC ADRENALECTOMY IN PATIENTS WITH PRIMARY ALDOSTERONISM Hayato Yamamoto, Naoki Fujita, Shingo Hatakeyama, Atsushi Imai, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, and Chikara Ohyama Hayato YamamotoHayato Yamamoto More articles by this author , Naoki FujitaNaoki Fujita More articles by this author , Shingo HatakeyamaShingo Hatakeyama More articles by this author , Atsushi ImaiAtsushi Imai More articles by this author , Takahiro YoneyamaTakahiro Yoneyama More articles by this author , Yasuhiro HashimotoYasuhiro Hashimoto More articles by this author , Takuya KoieTakuya Koie More articles by this author , and Chikara OhyamaChikara Ohyama More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2447AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To identify risk factors, including aortic calcification, for persistent hypertension in primary aldosteronism (PA) patients who underwent laparoscopic adrenalectomies. METHODS Between October 2000 and October 2015, we performed consecutive 101 laparoscopic adrenalectomies for unilateral PA patients. Of those, 95 patients who had at least one year follow-up periods were included. The patients were divided into two groups based on whether they had normal blood pressure without antihypertensive medications (resolved group) or still required medications (unresolved group) at one year after surgery. Variables included age, gender, body mass index, history of hypertension, dosage of antihypertensive medication score, presence of type 2 diabetes, subclinical Cushing syndrome, preoperative renal function, aldosteronoma resolution score (ARS), and abdominal calcification index (ACI). Univariate and multivariate logistic regression analyses were used to assess independent risk factors for persistent hypertension one year after surgery. RESULTS The complete resolution of hypertension without antihypertensive medication one year after adrenalectomy was 36/95 (38%). Preoperative antihypertensive medication score, systolic blood pressure, ACI were significantly higher, and ARS were significantly lower in the unresolved group than in the resolved group. Using multivariate logistic regression analysis, independent risk factors significantly correlating with persistent hypertension one year after surgery were ARS and ACI. CONCLUSIONS Adrenalectomy improved blood pressure and the need for antihypertensive medications, whereas ARS and ACI were potential independent risk factors for persistent hypertension one year after adrenalectomy. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e128 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Hayato Yamamoto More articles by this author Naoki Fujita More articles by this author Shingo Hatakeyama More articles by this author Atsushi Imai More articles by this author Takahiro Yoneyama More articles by this author Yasuhiro Hashimoto More articles by this author Takuya Koie More articles by this author Chikara Ohyama More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...