MP11-19 IT'S ALL IN THE NAME: DOES NOMENCLATURE FOR INDOLENT PROSTATE CANCER IMPACT MANAGEMENT AND ANXIETY?

Abstract

You have accessJournal of UrologyProstate Cancer: Staging (MP11)1 Sep 2021MP11-19 IT'S ALL IN THE NAME: DOES NOMENCLATURE FOR INDOLENT PROSTATE CANCER IMPACT MANAGEMENT AND ANXIETY? Anuj S. Desai, Matthew T. Hudnall, Kyle P. Tsai, Adam B. Weiner, Amanda X. Vo, Oliver S. Ko, Stephen Jan, Edward M. Schaeffer, and Shilajit D. Kundu Anuj S. DesaiAnuj S. Desai More articles by this author , Matthew T. HudnallMatthew T. Hudnall More articles by this author , Kyle P. TsaiKyle P. Tsai More articles by this author , Adam B. WeinerAdam B. Weiner More articles by this author , Amanda X. VoAmanda X. Vo More articles by this author , Oliver S. KoOliver S. Ko More articles by this author , Stephen JanStephen Jan More articles by this author , Edward M. SchaefferEdward M. Schaeffer More articles by this author , and Shilajit D. KunduShilajit D. Kundu More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000001984.19AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Despite consensus guidelines, many men with low-grade prostate cancer are not managed with active surveillance. Patient perception of the nomenclature used to describe low-grade prostate cancers may partly explain this discrepancy. METHODS: A randomized online survey was administered to men without a history of prostate cancer, presenting a hypothetical clinical scenario where the man is given a new diagnosis of low-grade prostate cancer. Using three terms for low-grade prostate cancer, “Gleason 6 out of 10 prostate cancer”, “Grade group 1 out of 5 prostate cancer”, or “Indolent lesion of epithelial origin,” we tested whether diagnosis nomenclature was associated with management preference and diagnosis-related anxiety immediately following the diagnosis and after receiving disease-specific education. Ratings were made on a 1-to-100 scale and adjusted for participant characteristics through multivariable linear regression. RESULTS: Of the 718 participants, 648 were White (90.2%) and the mean age was 61 (standard deviation 11) years. Most participants were college educated and approximately half had annual incomes >$75,000. There were no differences in baseline characteristics between groups. Compared to “Gleason 6 out of 10 prostate cancer,” the term “Grade Group 1 out of 5 prostate cancer” was associated with lower preference for immediate treatment versus active surveillance (b=–9.3, 95% CI [–14.4 to –4.2], p<0.001) and lower diagnosis-related anxiety (b=-8.3, 95% CI [-12.8 to -3.8], p<0.001) at time of initial diagnosis. Differences decreased as participants received more disease-specific education. “Indolent lesion of epithelial origin,” a suggested alternative term for indolent tumors, was not associated with differences in anxiety or preference for active surveillance. CONCLUSIONS: Within a hypothetical clinical scenario, nomenclature for low-grade prostate cancer affects initial perception of the disease and may alter subsequent decision-making, including preference for active surveillance. Disease-specific education reduces the differential impact of nomenclature use, reaffirming the importance of comprehensive counseling between the clinician and patient. Source of Funding: SPORE prostate cancer P50 CA180995 © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e186-e187 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Anuj S. Desai More articles by this author Matthew T. Hudnall More articles by this author Kyle P. Tsai More articles by this author Adam B. Weiner More articles by this author Amanda X. Vo More articles by this author Oliver S. Ko More articles by this author Stephen Jan More articles by this author Edward M. Schaeffer More articles by this author Shilajit D. Kundu More articles by this author Expand All Advertisement Loading ...