MP10-12 FOLLOW-UP 24-URINE STUDIES DURING AND POST-COVID-19 PANDEMIC

Abstract

You have accessJournal of UrologyCME1 Apr 2023MP10-12 FOLLOW-UP 24-URINE STUDIES DURING AND POST-COVID-19 PANDEMIC Jennifer Lu, Brian Shkolnik, Kelley Zhao, Pankti Kothari, Scott Herfel, Hailey Schulsinger, Yefim Sheynkin, and David Schulsinger Jennifer LuJennifer Lu More articles by this author , Brian ShkolnikBrian Shkolnik More articles by this author , Kelley ZhaoKelley Zhao More articles by this author , Pankti KothariPankti Kothari More articles by this author , Scott HerfelScott Herfel More articles by this author , Hailey SchulsingerHailey Schulsinger More articles by this author , Yefim SheynkinYefim Sheynkin More articles by this author , and David SchulsingerDavid Schulsinger More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003225.12AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: In New York State, March 16, 2020 marked the end of any in-restaurant dining due to the COVID-19 pandemic. The general population was forced to do more cooking at home and less dining out. Dietary modifications like this are considered first line therapy for calcium stone formers due to an effort to reduce dietary sodium intake which is known to affect lithogenic risk factors including hypernatriuria and hypercalciuria. This study aims to see if dietary changes made during the pandemic changed the risk of stone disease as evidenced in 24-hour urine studies and if these changes ceased after the end of widespread shutdowns. METHODS: All patients with nephrolithiasis seen for an outpatient visit from April 1, 2020-December 31, 2020 were queried and included if they had a 24-hour urine study pre-COVID (before March 16, 2020) and during-COVID (March 16, 2020-December 31, 2020); a post-COVID study was included if available (January 1, 2021- October 31, 2022). Values were compared using paired, 2-tailed t-tests. RESULTS: 93 patients (54 males, 39 females, mean age 60.1) were studied pre-COVID, during-COVID, and post-COVID time periods with 24-hour urine studies. Stone analysis revealed calcium oxalate (61%), calcium phosphate (15%), uric acid (15%), other (9%). The 24-hour urine revealed a significant reduction in urinary sodium (uNa) and urinary calcium (uCa) in these patients. uNa levels decreased from 166.15±7.5 mEq/L pre-COVID to 149.09±7.6 mEq/L during-COVID (p=0.015) and maintained improved at 138.55±6.83 mEq/L post-COVID era (p=0.0035). uCa levels decreased from 214.18±13.05 mEq/L pre-COVID to 191.48±13.03 mEq/L during-COVID levels (p=0.010) and remained improved at 185.33±12.61 mEq/L post-COVID (p=0.012). There were no significant differences in 24-hour urine total volume, magnesium, or citrate levels. CONCLUSIONS: During the COVID-19 lockdown, dietary choices limited to home cooked meals allowed patients to better identify their food choices. This study demonstrates that known urinary risk factors for lithogenesis, such as urinary sodium and calcium, improved during the lockdown and these improvements were maintained even after restrictions in restaurants were lifted. Moving forward, it will be imperative to monitor patient’s 24-hour urine to ensure these dietary modifications are continued in the post-pandemic era and to see if these improved urinary parameters will impact stone formation in these patients. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e119 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Jennifer Lu More articles by this author Brian Shkolnik More articles by this author Kelley Zhao More articles by this author Pankti Kothari More articles by this author Scott Herfel More articles by this author Hailey Schulsinger More articles by this author Yefim Sheynkin More articles by this author David Schulsinger More articles by this author Expand All Advertisement PDF downloadLoading ...