MP09-15 INVESTIGATION OF FROZEN SECTION BIOPSY UTILIZATION IN MAGNETIC RESONANCE IMAGING–ULTRASONOGRAPHY FUSION-TARGETED PROSTATE BIOPSY FOR HIGH-RISK PROSTATE CANCER

Abstract

You have accessJournal of UrologyCME1 May 2022MP09-15 INVESTIGATION OF FROZEN SECTION BIOPSY UTILIZATION IN MAGNETIC RESONANCE IMAGING–ULTRASONOGRAPHY FUSION-TARGETED PROSTATE BIOPSY FOR HIGH-RISK PROSTATE CANCER Seung Bin Kim, Jong Hyun Tae, Hyun Jung Jin, Tae Il Noh, Ji Sung Shim, Seok Ho Kang, Jun Cheon, Jeong Gu Lee, and Sung Gu Kang Seung Bin KimSeung Bin Kim More articles by this author , Jong Hyun TaeJong Hyun Tae More articles by this author , Hyun Jung JinHyun Jung Jin More articles by this author , Tae Il NohTae Il Noh More articles by this author , Ji Sung ShimJi Sung Shim More articles by this author , Seok Ho KangSeok Ho Kang More articles by this author , Jun CheonJun Cheon More articles by this author , Jeong Gu LeeJeong Gu Lee More articles by this author , and Sung Gu KangSung Gu Kang More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002531.15AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The current guidelines for targeted prostate biopsy recommend an additional systematic biopsy regardless of clinical risk assessment.To evaluate frozen section biopsy utilization in targeted prostate biopsy to omit systematic biopsies in cases of positive frozen section results of patients with clinical features suggestive of high-risk prostate cancer. METHODS: In this prospective, single-center study, we enrolled patients with a Prostate Imaging-Reporting and Data System (PI-RADS) 5 lesion on magnetic resonance imaging (MRI) with clinical evidence suggestive of high-risk prostate cancer (either an extracapsular extension or prostate-specific antigen level >20 ng/ml). All patients underwent 2–4 core targeted biopsies utilizing frozen section biopsy with immediate results, allowing patients with a positive result to omit a systematic biopsy. In case of a negative result, additional systematic biopsies were performed. The primary endpoint was the detection rate of targeted biopsy. Patient demographics, clinical variables were analyzed using SPSS version 20. RESULTS: Sixty-six patients were enrolled in this study. Among them, 63 patients were diagnosed with cancer without the need for an additional systematic biopsy. Three patients were non-diagnostic with target biopsy alone. Hence an additional systematic biopsy was performed. Two of these patients were diagnosed with prostate cancer and one tested negative for cancer. CONCLUSIONS: In this report we looked into the necessity of taking a routine systematic biopsy in patients with high risk features of prostate cancer. We found that utilizing frozen section biopsy for targeted biopsy reduces unneccessary systematic biopsy in 97% of cases and still provides a means for systematic biopsy when targeted biopsy alone fails to make the diagnosis. Source of Funding: None © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e141 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Seung Bin Kim More articles by this author Jong Hyun Tae More articles by this author Hyun Jung Jin More articles by this author Tae Il Noh More articles by this author Ji Sung Shim More articles by this author Seok Ho Kang More articles by this author Jun Cheon More articles by this author Jeong Gu Lee More articles by this author Sung Gu Kang More articles by this author Expand All Advertisement PDF DownloadLoading ...