MP08-19 COMORBID CONDITIONS ASSOCIATED WITH NOCTURNAL POLYURIA: RESULTS FROM THE EPIDEMIOLOGY OF NOCTURNAL POLYURIA (EpiNP) STUDY

Abstract

You have accessJournal of UrologyBladder & Urethra: Anatomy, Physiology & Pharmacology (MP08)1 Sep 2021MP08-19 COMORBID CONDITIONS ASSOCIATED WITH NOCTURNAL POLYURIA: RESULTS FROM THE EPIDEMIOLOGY OF NOCTURNAL POLYURIA (EpiNP) STUDY Christopher R. Chapple, Matt T. Rosenberg, Elizabeth D. Bacci, Anne B. Brooks, Fredrik L. Andersson, and JLH Ruud Bosch Christopher R. ChappleChristopher R. Chapple More articles by this author , Matt T. RosenbergMatt T. Rosenberg More articles by this author , Elizabeth D. BacciElizabeth D. Bacci More articles by this author , Anne B. BrooksAnne B. Brooks More articles by this author , Fredrik L. AnderssonFredrik L. Andersson More articles by this author , and JLH Ruud BoschJLH Ruud Bosch More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000001981.19AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To assess the prevalence of nocturnal polyuria (NP) in a large epidemiologic study of a US population-representative sample of men (M) and women (W) ≥30 years (The EpiNP Study; NCT: 04125186). METHODS: Participants were recruited via an online panel. Consenting participants completed the baseline EpiNP survey online (Lower Urinary Tract Symptoms [LUTS] Tool, comorbidities, burden and health-related quality of life measures). All who reported ≥2 voids/night and a random sample of 100 respondents each reporting 0 or 1 void/night were sent urine collection containers and asked to complete a 3-day web-based bladder diary recording the time, volume, and urgency rating of each void. Pure NP (NP without underlying causes) was defined by calculating the proportion of urine production that occurred during nocturnal hours, using nocturnal urine production of >90 mL/h (NUP90) and the Nocturnal Polyuria Index (NPI33) threshold of >0.33. Subgroups were created: Pure NP (NP with no underlying cause), NP with symptoms suggestive of overactive bladder (NPOAB) or bladder outlet obstruction (NPBOO; M only), NP due to other comorbidities (diabetes, hypertension, heart disease, sleep apnea), and no NP (did not meet NUP90 or NPI33). Clinical and urologic comorbid conditions were summarized by NP group. RESULTS: 10,190 completed baseline survey (4,900 M/5,290 W); 1,766 (718 M/1,048 W) completed the bladder diary for 3 days. Pure NP prevalence was lower among M (NUP90: 3.2%; NPI33: 5.5%) than W (NUP90: 5.5%; NPI33: 13.0%). For both M and W, participants classified as Pure NP had the lowest mean age (M: 49.9; W: 50.8 years), smaller mean waist circumference (M: 39.4; W: 36.7 cm) and fewest with BMI ≥30 compared to other NP groups (table). Pure NP group reported few other urologic conditions compared to other NP subgroups and M had more urologic conditions than W. M tended to have more medical comorbidities associated with other NP subgroups than W except for anxiety, depression, and arthritis. CONCLUSIONS: This is the first ever population-based prevalence study of NP to examine comorbidities for men and women. Pure NP was associated lower age, as well as fewer comorbid or urologic conditions than other NP groups. Source of Funding: Ferring provided the funding for this study © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e158-e158 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Christopher R. Chapple More articles by this author Matt T. Rosenberg More articles by this author Elizabeth D. Bacci More articles by this author Anne B. Brooks More articles by this author Fredrik L. Andersson More articles by this author JLH Ruud Bosch More articles by this author Expand All Advertisement Loading ...